Uranium


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity Increases phenotype PMID:27544493
GO:0006041 Glucosamine metabolic process Affects phenotype PMID:35525329
GO:0006090 Pyruvate metabolic process Affects phenotype PMID:35525329
GO:0006306 Dna methylation Affects phenotype PMID:29024790
GO:0006631 Fatty acid metabolic process Affects phenotype PMID:35525329
GO:0006703 Estrogen biosynthetic process Decreases phenotype PMID:27544493
GO:0007283 Spermatogenesis Decreases phenotype PMID:40372707
GO:0008217 Regulation of blood pressure Affects phenotype PMID:20889151
GO:0008219 Cell death Increases phenotype PMID:30076899
GO:0008652 Amino acid biosynthetic process Affects phenotype PMID:35525329
GO:0009308 Amine metabolic process Affects phenotype PMID:35525329
GO:0010493 Lewis a epitope biosynthetic process Affects phenotype PMID:35525329
GO:0010508 Positive regulation of autophagy Increases phenotype PMID:31120128
GO:0019369 Arachidonic acid metabolic process Affects phenotype PMID:35525329
GO:0019507 Pyridine metabolic process Affects phenotype PMID:35525329
GO:0019521 D-gluconate metabolic process Affects phenotype PMID:35525329
GO:0019752 Carboxylic acid metabolic process Affects phenotype PMID:35525329
GO:0030097 Hemopoiesis Affects phenotype PMID:20889151
GO:0030317 Flagellated sperm motility Decreases phenotype PMID:40372707
GO:0030502 Negative regulation of bone mineralization Increases phenotype PMID:31120128
GO:0035936 Testosterone secretion Decreases phenotype PMID:40372707
GO:0036269 Swimming behavior Decreases phenotype PMID:27639536
GO:0036343 Psychomotor behavior Decreases phenotype PMID:27639536
GO:0042431 Indole metabolic process Affects phenotype PMID:35525329
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:29477364; PMID:37270086
GO:0043420 Anthranilate metabolic process Affects phenotype PMID:35525329
GO:0044237 Cellular metabolic process Decreases phenotype PMID:35525329
GO:0045666 Positive regulation of neuron differentiation Decreases phenotype PMID:27639536
GO:0045780 Positive regulation of bone resorption Increases phenotype PMID:29477364
GO:0046470 Phosphatidylcholine metabolic process Affects phenotype PMID:35525329
GO:0046473 Phosphatidic acid metabolic process Affects phenotype PMID:35525329
GO:0060009 Sertoli cell development Decreases phenotype PMID:40372707
GO:0061351 Neural precursor cell proliferation Increases phenotype PMID:27639536
GO:0061370 Testosterone biosynthetic process Decreases phenotype PMID:27544493
GO:0072520 Seminiferous tubule development Decreases phenotype PMID:40372707
GO:1900745 Positive regulation of p38mapk cascade Increases phenotype PMID:29477364
GO:1905867 Epididymis development Decreases phenotype PMID:40372707
GO:2000786 Positive regulation of autophagosome assembly Increases phenotype PMID:31120128
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.