Nitrofen


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000165 Mapk cascade Increases phenotype PMID:15582350; PMID:17439724
GO:0001890 Placenta development Decreases phenotype PMID:24352370; PMID:26672737
GO:0002053 Positive regulation of mesenchymal cell proliferation Decreases phenotype PMID:26382659; PMID:26519041; PMID:27522124; PMID:27651373
GO:0003031 Detection of carbon dioxide Increases phenotype PMID:34502408
GO:0003032 Detection of oxygen Increases phenotype PMID:34502408
GO:0006915 Apoptotic process Increases phenotype PMID:15582350; PMID:17439724; PMID:17993583; PMID:20549697; PMID:22015466; PMID:23114405
GO:0006979 Response to oxidative stress Increases phenotype PMID:15582350
GO:0007049 Cell cycle Decreases phenotype PMID:17439724
GO:0008283 Cell population proliferation Affects phenotype PMID:17439724; PMID:20549697; PMID:23050982; PMID:25487476; PMID:29196881
GO:0030324 Lung development Decreases phenotype PMID:23354098; PMID:30995255
GO:0033864 Positive regulation of nad(p)h oxidase activity Increases phenotype PMID:26534761
GO:0034633 Retinol transport Decreases phenotype PMID:26672737
GO:0042572 Retinol metabolic process Increases phenotype PMID:24972641; PMID:26672737
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:26649853
GO:0045851 Ph reduction Increases phenotype PMID:34502408
GO:0048286 Lung alveolus development Decreases phenotype PMID:34502408
GO:0051451 Myoblast migration Decreases phenotype PMID:27480986
GO:0051881 Regulation of mitochondrial membrane potential Decreases phenotype PMID:17439724
GO:0060437 Lung growth Decreases phenotype PMID:24352370; PMID:30106123
GO:0060502 Epithelial cell proliferation involved in lung morphogenesis Decreases phenotype PMID:31843527
GO:0060539 Diaphragm development Decreases phenotype PMID:26519041
GO:0061046 Regulation of branching involved in lung morphogenesis Affects phenotype PMID:31843527
GO:0061112 Negative regulation of bud outgrowth involved in lung branching Increases phenotype PMID:30106123
GO:0061448 Connective tissue development Decreases phenotype PMID:27480986
GO:0070994 Detection of oxidative stress Increases phenotype PMID:34502408
GO:1904655 Positive regulation of lung alveolus development Decreases phenotype PMID:26672737
GO:1905111 Positive regulation of pulmonary blood vessel remodeling Increases phenotype PMID:30418988
GO:2000439 Positive regulation of monocyte extravasation Increases phenotype PMID:30418988
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.