| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0001824 | Blastocyst development | Decreases phenotype | PMID:34014595 |
| GO:0004364 | Glutathione transferase activity | Decreases phenotype | PMID:32270456 |
| GO:0004457 | Lactate dehydrogenase activity | Increases phenotype | PMID:24581381 |
| GO:0004602 | Glutathione peroxidase activity | Decreases phenotype | PMID:24581381; PMID:32270456 |
| GO:0004784 | Superoxide dismutase activity | Decreases phenotype | PMID:24581381; PMID:32270456 |
| GO:0006695 | Cholesterol biosynthetic process | Affects phenotype | PMID:24581381 |
| GO:0006750 | Glutathione biosynthetic process | Decreases phenotype | PMID:24248738 |
| GO:0006915 | Apoptotic process | Increases phenotype | PMID:34014595 |
| GO:0006974 | Cellular response to dna damage stimulus | Increases phenotype | PMID:34014595 |
| GO:0007283 | Spermatogenesis | Affects phenotype | PMID:34014595 |
| GO:0010942 | Positive regulation of cell death | Increases phenotype | PMID:20654549 |
| GO:0016042 | Lipid catabolic process | Increases phenotype | PMID:24581381; PMID:32270456; PMID:34014595 |
| GO:0019853 | L-ascorbic acid biosynthetic process | Decreases phenotype | PMID:24581381 |
| GO:0046449 | Creatinine metabolic process | Affects phenotype | PMID:32270456 |
| GO:0061370 | Testosterone biosynthetic process | Decreases phenotype | PMID:24581381 |
| GO:0061827 | Sperm head | Affects phenotype | PMID:34014595 |
| GO:0070265 | Necrotic cell death | Increases phenotype | PMID:32270456 |
| GO:0097722 | Sperm motility | Decreases phenotype | PMID:34014595 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.