Tris(1,3-dichloro-2-propyl)phosphate


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000266 Mitochondrial fission Affects phenotype PMID:36115506
GO:0001655 Urogenital system development Affects phenotype PMID:32360330
GO:0001774 Microglial cell activation Increases phenotype PMID:31894355
GO:0001958 Endochondral ossification Decreases phenotype PMID:33367866
GO:0005739 Mitochondrion Increases phenotype PMID:38518089
GO:0006497 Protein lipidation Increases phenotype PMID:36375964
GO:0006754 Atp biosynthetic process Affects phenotype PMID:28641197
GO:0006914 Autophagy Increases phenotype PMID:28025121
GO:0006915 Apoptotic process Increases phenotype PMID:28025121; PMID:28641197; PMID:31894355; PMID:36375964
GO:0007005 Mitochondrion organization Affects phenotype PMID:35135005
GO:0007040 Lysosome organization Increases phenotype PMID:35135005
GO:0007204 Positive regulation of cytosolic calcium ion concentration Increases phenotype PMID:27816613
GO:0008219 Cell death Increases phenotype PMID:26179874; PMID:28181390
GO:0008283 Cell population proliferation Decreases phenotype PMID:28181390
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:26979758
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:28959647; PMID:29783866; PMID:30842366
GO:0008923 Lysine decarboxylase activity Decreases phenotype PMID:25264276
GO:0009060 Aerobic respiration Increases phenotype PMID:30966736
GO:0010001 Glial cell differentiation Increases phenotype PMID:28851516
GO:0010918 Positive regulation of mitochondrial membrane potential Affects phenotype PMID:27816613; PMID:38331085
GO:0010942 Positive regulation of cell death Increases phenotype PMID:28959647
GO:0016477 Cell migration Decreases phenotype PMID:33969458
GO:0030182 Neuron differentiation Increases phenotype PMID:28851516
GO:0030539 Male genitalia development Affects phenotype PMID:33280148
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:26979758
GO:0034976 Response to endoplasmic reticulum stress Increases phenotype PMID:27816613
GO:0040018 Positive regulation of multicellular organism growth Increases phenotype PMID:32360330
GO:0042632 Cholesterol homeostasis Decreases phenotype PMID:30966736
GO:0042701 Progesterone secretion Affects phenotype PMID:36115506
GO:0043005 Neuron projection Decreases phenotype PMID:24717766
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:24717766; PMID:27816613; PMID:30842366; PMID:38331085
GO:0044237 Cellular metabolic process Decreases phenotype PMID:28025121; PMID:28641197; PMID:36115506
GO:0045851 Ph reduction Increases phenotype PMID:28025121
GO:0045930 Negative regulation of mitotic cell cycle Increases phenotype PMID:28959647; PMID:30842366
GO:0046034 Atp metabolic process Affects phenotype PMID:30966736; PMID:36115506
GO:0048709 Oligodendrocyte differentiation Decreases phenotype PMID:33969458
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:28641197
GO:0051882 Mitochondrial depolarization Increases phenotype PMID:36115506
GO:0051901 Positive regulation of mitochondrial depolarization Increases phenotype PMID:34036598
GO:0052689 Carboxylic ester hydrolase activity Decreases phenotype PMID:32511959
GO:0055074 Calcium ion homeostasis Affects phenotype PMID:28181390
GO:0060612 Adipose tissue development Increases phenotype PMID:36493961
GO:0070328 Triglyceride homeostasis Decreases phenotype PMID:30966736
GO:0070343 White fat cell proliferation Increases phenotype PMID:36493961
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:28025121; PMID:36115506
GO:0140042 Lipid droplet formation Affects phenotype PMID:35135005
GO:1902237 Positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Increases phenotype PMID:38331085
GO:1902476 Chloride transmembrane transport Decreases phenotype PMID:29783866
GO:1903407 Negative regulation of p-type sodium:potassium-exchanging transporter activity Increases phenotype PMID:29783866
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:27816613; PMID:30842366; PMID:35135005; PMID:38603619
GO:2000866 Positive regulation of estradiol secretion Increases phenotype PMID:38603619
GO:2000872 Positive regulation of progesterone secretion Increases phenotype PMID:38603619
GO:2001170 Negative regulation of atp biosynthetic process Increases phenotype PMID:38331085
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.