8-Bromo cyclic adenosine monophosphate


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0005249 Voltage-gated potassium channel activity Increases phenotype PMID:29183753
GO:0005980 Glycogen catabolic process Increases phenotype PMID:2982682
GO:0006309 Apoptotic dna fragmentation Increases phenotype PMID:10642304
GO:0006694 Steroid biosynthetic process Affects phenotype PMID:34896276
GO:0006701 Progesterone biosynthetic process Increases phenotype PMID:24740604
GO:0006702 Androgen biosynthetic process Increases phenotype PMID:27388148; PMID:31184881; PMID:31184881; PMID:31499053; PMID:31499053; PMID:33862173
GO:0006936 Muscle contraction Increases phenotype PMID:39151807
GO:0006949 Syncytium formation Increases phenotype PMID:32028606
GO:0007268 Chemical synaptic transmission Increases phenotype PMID:15813995
GO:0008209 Androgen metabolic process Affects phenotype PMID:27148549; PMID:32898603
GO:0008283 Cell population proliferation Decreases phenotype PMID:11802967
GO:0010893 Positive regulation of steroid biosynthetic process Increases phenotype PMID:29560447
GO:0015562 Efflux transmembrane transporter activity Decreases phenotype PMID:30610963
GO:0016042 Lipid catabolic process Increases phenotype PMID:11517154; PMID:16077714; PMID:18328801
GO:0030154 Cell differentiation Increases phenotype PMID:16997883
GO:0032310 Prostaglandin secretion Increases phenotype PMID:26945481
GO:0033327 Leydig cell differentiation Increases phenotype PMID:22927073
GO:0033344 Cholesterol efflux Increases phenotype PMID:17478430
GO:0035935 Androgen secretion Increases phenotype PMID:33581290
GO:0042311 Vasodilation Increases phenotype PMID:7586449
GO:0042701 Progesterone secretion Increases phenotype PMID:31132478
GO:0046697 Decidualization Increases phenotype PMID:26945481
GO:0046982 Protein heterodimerization activity Decreases phenotype PMID:29669941
GO:0061370 Testosterone biosynthetic process Increases phenotype PMID:27388148
GO:0140115 Export across plasma membrane Decreases phenotype PMID:30610963
GO:2000836 Positive regulation of androgen secretion Increases phenotype PMID:37419161; PMID:37419161; PMID:37783241; PMID:37783241
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.