| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0006695 | Cholesterol biosynthetic process | Increases phenotype | PMID:30935970 |
| GO:0006699 | Bile acid biosynthetic process | Increases phenotype | PMID:30935970 |
| GO:0008283 | Cell population proliferation | Increases phenotype | PMID:15465647; PMID:25370011 |
| GO:0008285 | Negative regulation of cell population proliferation | Increases phenotype | PMID:25835094 |
| GO:0008610 | Lipid biosynthetic process | Increases phenotype | PMID:30935970 |
| GO:0019432 | Triglyceride biosynthetic process | Increases phenotype | PMID:30935970 |
| GO:0030308 | Negative regulation of cell growth | Increases phenotype | PMID:25835094 |
| GO:0032125 | Micronucleus organization | Increases phenotype | PMID:31733235 |
| GO:0036124 | Histone h3-k9 trimethylation | Decreases phenotype | PMID:26519613 |
| GO:0042593 | Glucose homeostasis | Increases phenotype | PMID:24231106; PMID:25734695; PMID:31306034 |
| GO:0043065 | Positive regulation of apoptotic process | Increases phenotype | PMID:25835094 |
| GO:0046326 | Positive regulation of glucose import | Affects phenotype | PMID:24231106 |
| GO:0046627 | Negative regulation of insulin receptor signaling pathway | Affects phenotype | PMID:24231106 |
| GO:0048874 | Host-mediated regulation of intestinal microbiota composition | Affects phenotype | PMID:30935970 |
| GO:0060612 | Adipose tissue development | Increases phenotype | PMID:25734695 |
| GO:0072593 | Reactive oxygen species metabolic process | Increases phenotype | PMID:25370011 |
| GO:0080182 | Histone h3-k4 trimethylation | Increases phenotype | PMID:26519613 |
| GO:1901224 | Positive regulation of nik/nf-kappab signaling | Increases phenotype | PMID:26519613 |
| GO:1902884 | Positive regulation of response to oxidative stress | Affects phenotype | PMID:24231106 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.