| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0005248 | Voltage-gated sodium channel activity | Decreases phenotype | PMID:31250031 |
| GO:0005249 | Voltage-gated potassium channel activity | Decreases phenotype | PMID:31250031 |
| GO:0006915 | Apoptotic process | Increases phenotype | PMID:34303733 |
| GO:0006954 | Inflammatory response | Increases phenotype | PMID:30445053 |
| GO:0008283 | Cell population proliferation | Increases phenotype | PMID:20962025; PMID:27026707 |
| GO:0008284 | Positive regulation of cell population proliferation | Increases phenotype | PMID:29307715 |
| GO:0008285 | Negative regulation of cell population proliferation | Increases phenotype | PMID:23526725; PMID:30196065 |
| GO:0016477 | Cell migration | Increases phenotype | PMID:35007301 |
| GO:0030282 | Bone mineralization | Affects phenotype | PMID:29428397 |
| GO:0033148 | Positive regulation of intracellular estrogen receptor signaling pathway | Increases phenotype | PMID:27473340 |
| GO:0036336 | Dendritic cell migration | Increases phenotype | PMID:30445053 |
| GO:0036474 | Cell death in response to hydrogen peroxide | Affects phenotype | PMID:23526725 |
| GO:0044237 | Cellular metabolic process | Decreases phenotype | PMID:34303733; PMID:36863540 |
| GO:0045880 | Positive regulation of smoothened signaling pathway | Increases phenotype | PMID:29307715 |
| GO:0050665 | Hydrogen peroxide biosynthetic process | Increases phenotype | PMID:20962025 |
| GO:0072677 | Eosinophil migration | Increases phenotype | PMID:30445053 |
| GO:0086003 | Cardiac muscle cell contraction | Increases phenotype | PMID:25723814 |
| GO:1903409 | Reactive oxygen species biosynthetic process | Increases phenotype | PMID:20962025 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.