Azacytidine


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000080 Mitotic g1 phase Affects phenotype PMID:32278510
GO:0000086 G2/m transition of mitotic cell cycle Decreases phenotype PMID:16427046
GO:0001503 Ossification Decreases phenotype PMID:39531065
GO:0002320 Lymphoid progenitor cell differentiation Decreases phenotype PMID:39331569
GO:0006306 Dna methylation Affects phenotype PMID:17686055; PMID:17686055; PMID:18790780; PMID:18033690; PMID:18790780; PMID:18790780; PMID:20861661; PMID:3258330; PMID:6159882; PMID:6197180; PMID:7511991
GO:0006309 Apoptotic dna fragmentation Increases phenotype PMID:1282508; PMID:7686540; PMID:7686540
GO:0006915 Apoptotic process Increases phenotype PMID:1282508; PMID:7686540; PMID:18443271; PMID:18829727; PMID:25953102; PMID:32278510
GO:0006954 Inflammatory response Increases phenotype PMID:28392331
GO:0007049 Cell cycle Decreases phenotype PMID:20607034; PMID:7679929
GO:0008219 Cell death Increases phenotype PMID:24518598; PMID:27099147
GO:0008283 Cell population proliferation Decreases phenotype PMID:20607034; PMID:25953102; PMID:39531065; PMID:7679929
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:29200404
GO:0010424 Dna methylation on cytosine within a cg sequence Decreases phenotype PMID:33536392
GO:0010918 Positive regulation of mitochondrial membrane potential Decreases phenotype PMID:28942281
GO:0010942 Positive regulation of cell death Increases phenotype PMID:25015661
GO:0019627 Urea metabolic process Increases phenotype PMID:27590069
GO:0030154 Cell differentiation Decreases phenotype PMID:18033690
GO:0031175 Neuron projection development Decreases phenotype PMID:33454822
GO:0032776 Dna methylation on cytosine Increases phenotype PMID:33454822
GO:0042554 Superoxide anion generation Increases phenotype PMID:32278510
GO:0042692 Muscle cell differentiation Increases phenotype PMID:28298639
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:9813173
GO:0043525 Positive regulation of neuron apoptotic process Increases phenotype PMID:16427046
GO:0043970 Histone h3-k9 acetylation Decreases phenotype PMID:32278510
GO:0044028 Dna hypomethylation Increases phenotype PMID:27132804
GO:0044237 Cellular metabolic process Decreases phenotype PMID:32278510
GO:0048386 Positive regulation of retinoic acid receptor signaling pathway Increases phenotype PMID:26820057
GO:0060612 Adipose tissue development Increases phenotype PMID:3891103
GO:0070265 Necrotic cell death Increases phenotype PMID:32278510
GO:0070368 Positive regulation of hepatocyte differentiation Increases phenotype PMID:27590069
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:32278510
GO:0072677 Eosinophil migration Increases phenotype PMID:28392331
GO:0072719 Cellular response to cisplatin Increases phenotype PMID:36336710
GO:0090398 Cellular senescence Increases phenotype PMID:39531065
GO:1901537 Positive regulation of dna demethylation Affects phenotype PMID:33536392
GO:1903047 Mitotic cell cycle process Affects phenotype PMID:32278510
GO:1990138 Neuron projection extension Decreases phenotype PMID:31652400
GO:2001170 Negative regulation of atp biosynthetic process Increases phenotype PMID:28942281
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.