| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0000737 | Dna catabolic process, endonucleolytic | Increases phenotype | PMID:36995427 |
| GO:0001516 | Prostaglandin biosynthetic process | Decreases phenotype | PMID:28267586 |
| GO:0006749 | Glutathione metabolic process | Affects phenotype | PMID:25656284 |
| GO:0006805 | Xenobiotic metabolic process | Increases phenotype | PMID:25745819; PMID:35597399 |
| GO:0008219 | Cell death | Increases phenotype | PMID:17636003 |
| GO:0010942 | Positive regulation of cell death | Increases phenotype | PMID:23397584; PMID:25656284 |
| GO:0016049 | Cell growth | Decreases phenotype | PMID:25091725 |
| GO:0016477 | Cell migration | Decreases phenotype | PMID:27413119 |
| GO:0032088 | Negative regulation of nf-kappab transcription factor activity | Affects phenotype | PMID:24352538 |
| GO:0032125 | Micronucleus organization | Increases phenotype | PMID:36995427 |
| GO:0035743 | Cd4-positive, alpha-beta t cell cytokine production | Increases phenotype | PMID:29644860 |
| GO:0036211 | Protein modification process | Increases phenotype | PMID:8723729 |
| GO:0042593 | Glucose homeostasis | Decreases phenotype | PMID:35786680 |
| GO:0043065 | Positive regulation of apoptotic process | Increases phenotype | PMID:24752500 |
| GO:0045429 | Positive regulation of nitric oxide biosynthetic process | Increases phenotype | PMID:25656284 |
| GO:0046621 | Negative regulation of organ growth | Decreases phenotype | PMID:35786680 |
| GO:0046622 | Positive regulation of organ growth | Increases phenotype | PMID:35786680 |
| GO:0060079 | Excitatory postsynaptic potential | Decreases phenotype | PMID:12076316 |
| GO:0070328 | Triglyceride homeostasis | Decreases phenotype | PMID:35786680 |
| GO:0070994 | Detection of oxidative stress | Increases phenotype | PMID:24486436 |
| GO:0099610 | Action potential initiation | Decreases phenotype | PMID:36375636 |
| GO:1901216 | Positive regulation of neuron death | Increases phenotype | PMID:25656284 |
| GO:1904178 | Negative regulation of adipose tissue development | Increases phenotype | PMID:35786680 |
| GO:1904179 | Positive regulation of adipose tissue development | Decreases phenotype | PMID:35786680 |
| GO:2000563 | Positive regulation of cd4-positive, alpha-beta t cell proliferation | Increases phenotype | PMID:29644860 |
| GO:2000786 | Positive regulation of autophagosome assembly | Increases phenotype | PMID:35786680 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.