Tcpobop


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0006094 Gluconeogenesis Decreases phenotype PMID:27180240; PMID:29550551
GO:0008283 Cell population proliferation Increases phenotype PMID:23626729; PMID:31170421
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:29893953
GO:0008610 Lipid biosynthetic process Increases phenotype PMID:27180240; PMID:29550551
GO:0010468 Regulation of gene expression Affects phenotype PMID:38710495
GO:0010942 Positive regulation of cell death Increases phenotype PMID:33629115
GO:0019432 Triglyceride biosynthetic process Affects phenotype PMID:27180240
GO:0032964 Collagen biosynthetic process Increases phenotype PMID:29550551
GO:0035358 Regulation of peroxisome proliferator activated receptor signaling pathway Affects phenotype PMID:27413110
GO:0045793 Positive regulation of cell size Increases phenotype PMID:38710495
GO:0045815 Transcription initiation-coupled chromatin remodeling Affects phenotype PMID:31236583
GO:0071897 Dna biosynthetic process Increases phenotype PMID:27530964
GO:1900182 Positive regulation of protein localization to nucleus Increases phenotype PMID:31181217
GO:1902275 Regulation of chromatin organization Affects phenotype PMID:29617930
GO:2000347 Positive regulation of hepatocyte proliferation Increases phenotype PMID:29973476; PMID:29973476; PMID:38128062; PMID:38128062

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.