Pirinixic Acid


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity Increases phenotype PMID:27853831
GO:0006915 Apoptotic process Increases phenotype PMID:16434500; PMID:37046073
GO:0008219 Cell death Increases phenotype PMID:16239165
GO:0008283 Cell population proliferation Affects phenotype PMID:10951269; PMID:11162775; PMID:11162775; PMID:23626729; PMID:16434500; PMID:23626729; PMID:29626562; PMID:38734220; PMID:9348444
GO:0015908 Fatty acid transport Increases phenotype PMID:28903485
GO:0019395 Fatty acid oxidation Increases phenotype PMID:28903485
GO:0031323 Regulation of cellular metabolic process Affects phenotype PMID:28965233
GO:0031398 Positive regulation of protein ubiquitination Increases phenotype PMID:25285770
GO:0032436 Positive regulation of proteasomal ubiquitin-dependent protein catabolic process Decreases phenotype PMID:25285770
GO:0032930 Positive regulation of superoxide anion generation Increases phenotype PMID:25285770
GO:0044237 Cellular metabolic process Decreases phenotype PMID:39067772
GO:0045793 Positive regulation of cell size Increases phenotype PMID:28049043
GO:0045795 Positive regulation of cell volume Increases phenotype PMID:38734220
GO:0045834 Positive regulation of lipid metabolic process Increases phenotype PMID:36805544
GO:0051092 Positive regulation of nf-kappab transcription factor activity Increases phenotype PMID:25285770
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:37046073
GO:0140042 Lipid droplet formation Increases phenotype PMID:37046073
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Affects phenotype PMID:26168851
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.