Pcb 180


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001523 Retinoid metabolic process Increases phenotype PMID:33992733
GO:0001755 Neural crest cell migration Decreases phenotype PMID:26238599
GO:0002440 Production of molecular mediator of immune response Increases phenotype PMID:18995849
GO:0006897 Endocytosis Increases phenotype PMID:26141388
GO:0006973 Intracellular accumulation of glycerol Increases phenotype PMID:39793953
GO:0007612 Learning Affects phenotype PMID:32521479
GO:0007616 Long-term memory Decreases phenotype PMID:26480858
GO:0008283 Cell population proliferation Decreases phenotype PMID:25659934
GO:0016049 Cell growth Decreases phenotype PMID:29704545
GO:0030502 Negative regulation of bone mineralization Increases phenotype PMID:33992733
GO:0032204 Regulation of telomere maintenance Affects phenotype PMID:32300848
GO:0032637 Interleukin-8 production Affects phenotype PMID:22326254
GO:0042403 Thyroid hormone metabolic process Affects phenotype PMID:16079076; PMID:19750101
GO:0042445 Hormone metabolic process Affects phenotype PMID:17938741
GO:0043433 Negative regulation of dna-binding transcription factor activity Increases phenotype PMID:26022396
GO:0044027 Hypermethylation of cpg island Affects phenotype PMID:25585924
GO:0044255 Cellular lipid metabolic process Increases phenotype PMID:24978599
GO:0046621 Negative regulation of organ growth Increases phenotype PMID:33992733
GO:0046622 Positive regulation of organ growth Increases phenotype PMID:33992733
GO:0048589 Developmental growth Decreases phenotype PMID:21851983
GO:0050847 Progesterone receptor signaling pathway Decreases phenotype PMID:26022396
GO:0050890 Cognition Decreases phenotype PMID:18288320
GO:0070994 Detection of oxidative stress Increases phenotype PMID:25659934
GO:0098868 Bone growth Increases phenotype PMID:33992733
GO:2000610 Negative regulation of thyroid hormone generation Increases phenotype PMID:33992733
GO:2000612 Regulation of thyroid-stimulating hormone secretion Affects phenotype PMID:19750101
GO:2000865 Negative regulation of estradiol secretion Increases phenotype PMID:33992733
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.