Thimerosal


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001755 Neural crest cell migration Decreases phenotype PMID:26238599
GO:0001836 Release of cytochrome c from mitochondria Increases phenotype PMID:23145070
GO:0004784 Superoxide dismutase activity Increases phenotype PMID:36411272
GO:0006304 Dna modification Increases phenotype PMID:36411272
GO:0006749 Glutathione metabolic process Affects phenotype PMID:36411272
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:26989453
GO:0006754 Atp biosynthetic process Affects phenotype PMID:35435491
GO:0006915 Apoptotic process Increases phenotype PMID:23145070; PMID:24942245
GO:0006919 Activation of cysteine-type endopeptidase activity involved in apoptotic process Increases phenotype PMID:27660204
GO:0007009 Plasma membrane organization Decreases phenotype PMID:30503815
GO:0007268 Chemical synaptic transmission Affects phenotype PMID:24675092
GO:0007399 Nervous system development Decreases phenotype PMID:24675092
GO:0008283 Cell population proliferation Decreases phenotype PMID:23145070; PMID:24942245
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:29555536
GO:0010942 Positive regulation of cell death Increases phenotype PMID:27015953
GO:0016049 Cell growth Decreases phenotype PMID:30503815
GO:0018158 Protein oxidation Increases phenotype PMID:36411272
GO:0034440 Lipid oxidation Increases phenotype PMID:36411272
GO:0035176 Social behavior Decreases phenotype PMID:24675092
GO:0042417 Dopamine metabolic process Affects phenotype PMID:36411272
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:27660204
GO:0043967 Histone h4 acetylation Decreases phenotype PMID:27660204
GO:0044060 Regulation of endocrine process Affects phenotype PMID:24675092
GO:0044237 Cellular metabolic process Decreases phenotype PMID:38325586
GO:0044319 Wound healing, spreading of cells Decreases phenotype PMID:38325586
GO:0045930 Negative regulation of mitotic cell cycle Increases phenotype PMID:23145070; PMID:24942245
GO:0046902 Regulation of mitochondrial membrane permeability Affects phenotype PMID:24942245
GO:0048666 Neuron development Affects phenotype PMID:24675092
GO:0070997 Neuron death Increases phenotype PMID:24675092
GO:0072593 Reactive oxygen species metabolic process Increases phenotype PMID:36411272; PMID:38325586
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.