Alternariol


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0002539 Prostaglandin production involved in inflammatory response Increases phenotype PMID:30503586
GO:0004035 Alkaline phosphatase activity Increases phenotype PMID:31733320
GO:0004364 Glutathione transferase activity Affects phenotype PMID:25827405
GO:0004602 Glutathione peroxidase activity Decreases phenotype PMID:25827405
GO:0006171 Camp biosynthetic process Increases phenotype PMID:30503586
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:25827405
GO:0006914 Autophagy Increases phenotype PMID:25456271
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:25827405
GO:0007095 Mitotic g2 dna damage checkpoint signaling Increases phenotype PMID:26341179
GO:0008219 Cell death Increases phenotype PMID:26474839; PMID:26474839; PMID:28007639; PMID:28007639
GO:0008283 Cell population proliferation Decreases phenotype PMID:25456271
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:27401186; PMID:30503586
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:25496143
GO:0010694 Positive regulation of alkaline phosphatase activity Increases phenotype PMID:27401186
GO:0010942 Positive regulation of cell death Increases phenotype PMID:25072143; PMID:27422292
GO:0030163 Protein catabolic process Increases phenotype PMID:25456271
GO:0030284 Nuclear estrogen receptor activity Increases phenotype PMID:27481073
GO:0030308 Negative regulation of cell growth Increases phenotype PMID:25496143
GO:0034440 Lipid oxidation Increases phenotype PMID:25072143
GO:0036091 Positive regulation of transcription from rna polymerase ii promoter in response to oxidative stress Increases phenotype PMID:27422292
GO:0043032 Positive regulation of macrophage activation Increases phenotype PMID:39725263
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:25496143
GO:0044237 Cellular metabolic process Decreases phenotype PMID:31733320; PMID:35405071
GO:0045657 Positive regulation of monocyte differentiation Increases phenotype PMID:39725263
GO:0045807 Positive regulation of endocytosis Affects phenotype PMID:26341179
GO:0051901 Positive regulation of mitochondrial depolarization Increases phenotype PMID:25496143
GO:0090398 Cellular senescence Increases phenotype PMID:25456271
GO:1901671 Positive regulation of superoxide dismutase activity Increases phenotype PMID:25072143
GO:1902110 Positive regulation of mitochondrial membrane permeability involved in apoptotic process Increases phenotype PMID:25496143
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:26474839
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:25072143; PMID:26341179; PMID:27422292
GO:2000786 Positive regulation of autophagosome assembly Decreases phenotype PMID:26341179
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.