Kappa-Bifenthrin


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001516 Prostaglandin biosynthetic process Increases phenotype PMID:30102949
GO:0001659 Temperature homeostasis Affects phenotype PMID:30009846
GO:0002539 Prostaglandin production involved in inflammatory response Increases phenotype PMID:29793499
GO:0004602 Glutathione peroxidase activity Decreases phenotype PMID:29775722; PMID:30102949; PMID:32061760
GO:0004784 Superoxide dismutase activity Affects phenotype PMID:25149237; PMID:29775722; PMID:30102949; PMID:32408700
GO:0005248 Voltage-gated sodium channel activity Affects phenotype PMID:25521199
GO:0006693 Prostaglandin metabolic process Affects phenotype PMID:32061760
GO:0006694 Steroid biosynthetic process Affects phenotype PMID:34896276
GO:0006749 Glutathione metabolic process Affects phenotype PMID:32408700
GO:0006750 Glutathione biosynthetic process Affects phenotype PMID:25149237; PMID:29775722; PMID:30102949
GO:0006809 Nitric oxide biosynthetic process Increases phenotype PMID:29775722; PMID:30102949
GO:0006915 Apoptotic process Increases phenotype PMID:27916261; PMID:31734314
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:32408700
GO:0007283 Spermatogenesis Decreases phenotype PMID:32408700
GO:0007625 Grooming behavior Decreases phenotype PMID:29775722
GO:0008219 Cell death Decreases phenotype PMID:30102949
GO:0008283 Cell population proliferation Affects phenotype PMID:24938463; PMID:28251819
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:29149346; PMID:29793499
GO:0008344 Adult locomotory behavior Decreases phenotype PMID:30102949
GO:0010729 Positive regulation of hydrogen peroxide biosynthetic process Increases phenotype PMID:29793499
GO:0010917 Negative regulation of mitochondrial membrane potential Increases phenotype PMID:38040083
GO:0016042 Lipid catabolic process Increases phenotype PMID:25149237; PMID:29775722; PMID:30102949; PMID:32061760; PMID:32408700
GO:0016887 Atp hydrolysis activity Decreases phenotype PMID:29775722
GO:0018158 Protein oxidation Increases phenotype PMID:29775722; PMID:30102949; PMID:32408700
GO:0019432 Triglyceride biosynthetic process Increases phenotype PMID:29554630
GO:0030534 Adult behavior Affects phenotype PMID:30009846
GO:0031959 Mineralocorticoid receptor signaling pathway Increases phenotype PMID:29149346
GO:0034440 Lipid oxidation Increases phenotype PMID:29793499
GO:0035148 Tube formation Decreases phenotype PMID:31734314
GO:0036126 Sperm flagellum Affects phenotype PMID:32408700
GO:0044237 Cellular metabolic process Decreases phenotype PMID:31734314; PMID:32061760
GO:0045429 Positive regulation of nitric oxide biosynthetic process Increases phenotype PMID:29793499
GO:0046058 Camp metabolic process Affects phenotype PMID:34896276
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:32061760
GO:0050665 Hydrogen peroxide biosynthetic process Affects phenotype PMID:32061760
GO:0051091 Positive regulation of dna-binding transcription factor activity Increases phenotype PMID:28973306
GO:0061370 Testosterone biosynthetic process Affects phenotype PMID:32408700
GO:0061827 Sperm head Affects phenotype PMID:32408700
GO:0072520 Seminiferous tubule development Affects phenotype PMID:32408700
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:32061760; PMID:32408700
GO:0097225 Sperm midpiece Affects phenotype PMID:32408700
GO:0097722 Sperm motility Decreases phenotype PMID:32408700
GO:1901216 Positive regulation of neuron death Increases phenotype PMID:29793499
GO:1901670 Negative regulation of superoxide dismutase activity Increases phenotype PMID:29793499
GO:1901671 Positive regulation of superoxide dismutase activity Increases phenotype PMID:26071804
GO:1903283 Negative regulation of glutathione peroxidase activity Increases phenotype PMID:29793499
GO:1903407 Negative regulation of p-type sodium:potassium-exchanging transporter activity Increases phenotype PMID:30978409
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:25149237; PMID:27916261; PMID:29775722
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:26071804; PMID:29793499
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.