Pentachlorophenol


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000045 Autophagosome assembly Increases phenotype PMID:30597782
GO:0000080 Mitotic g1 phase Increases phenotype PMID:30905860
GO:0000084 Mitotic s phase Decreases phenotype PMID:30905860
GO:0001542 Ovulation from ovarian follicle Increases phenotype PMID:19368227
GO:0001890 Placenta development Affects phenotype PMID:30597782
GO:0002381 Immunoglobulin production involved in immunoglobulin-mediated immune response Increases phenotype PMID:24051191
GO:0005243 Gap junction channel activity Decreases phenotype PMID:26023933
GO:0006304 Dna modification Increases phenotype PMID:27207664; PMID:30874336
GO:0006497 Protein lipidation Increases phenotype PMID:30597782
GO:0006750 Glutathione biosynthetic process Increases phenotype PMID:30905860
GO:0006915 Apoptotic process Increases phenotype PMID:30905860
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:26739637
GO:0006997 Nucleus organization Affects phenotype PMID:30874336
GO:0008283 Cell population proliferation Decreases phenotype PMID:30905860
GO:0010942 Positive regulation of cell death Increases phenotype PMID:27207664
GO:0030521 Androgen receptor signaling pathway Increases phenotype PMID:19368227
GO:0032125 Micronucleus organization Increases phenotype PMID:33057863
GO:0032715 Negative regulation of interleukin-6 production Increases phenotype PMID:31542660
GO:0032755 Positive regulation of interleukin-6 production Increases phenotype PMID:31542660
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:19368227
GO:0042403 Thyroid hormone metabolic process Affects phenotype PMID:19750101
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:30590774
GO:0044237 Cellular metabolic process Decreases phenotype PMID:33057863; PMID:35476398
GO:0045930 Negative regulation of mitotic cell cycle Affects phenotype PMID:30905860
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:30590774; PMID:30905860
GO:0070365 Hepatocyte differentiation Increases phenotype PMID:26739637
GO:0098705 Copper ion import across plasma membrane Increases phenotype PMID:30590774
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:30905860
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Affects phenotype PMID:30590774
GO:2001269 Positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway Increases phenotype PMID:30590774
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.