Methylcholanthrene


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000212 Meiotic spindle organization Decreases phenotype PMID:31712135
GO:0001541 Ovarian follicle development Decreases phenotype PMID:31712135
GO:0001544 Initiation of primordial ovarian follicle growth Decreases phenotype PMID:27163632
GO:0001545 Primary ovarian follicle growth Decreases phenotype PMID:27163632
GO:0001546 Preantral ovarian follicle growth Decreases phenotype PMID:27163632
GO:0001547 Antral ovarian follicle growth Decreases phenotype PMID:27163632
GO:0001555 Oocyte growth Decreases phenotype PMID:31712135
GO:0004364 Glutathione transferase activity Increases phenotype PMID:19788401
GO:0006309 Apoptotic dna fragmentation Increases phenotype PMID:11999409; PMID:24814887
GO:0006750 Glutathione biosynthetic process Increases phenotype PMID:24814887
GO:0006805 Xenobiotic metabolic process Increases phenotype PMID:18347083; PMID:19903449; PMID:6135573
GO:0006915 Apoptotic process Increases phenotype PMID:11999409; PMID:31712135
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:27163632; PMID:31712135
GO:0006979 Response to oxidative stress Increases phenotype PMID:15621696
GO:0007281 Germ cell development Affects phenotype PMID:35487396
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:35487396
GO:0008209 Androgen metabolic process Increases phenotype PMID:19903449
GO:0008210 Estrogen metabolic process Affects phenotype PMID:35487396
GO:0008283 Cell population proliferation Affects phenotype PMID:10626785; PMID:24814887
GO:0008584 Male gonad development Affects phenotype PMID:35487396
GO:0016049 Cell growth Increases phenotype PMID:36807623
GO:0030728 Ovulation Decreases phenotype PMID:31712135
GO:0034440 Lipid oxidation Increases phenotype PMID:23712962
GO:0036211 Protein modification process Increases phenotype PMID:6135573; PMID:6547179
GO:0042178 Xenobiotic catabolic process Increases phenotype PMID:27917125; PMID:9929512
GO:0043970 Histone h3-k9 acetylation Affects phenotype PMID:29094188
GO:0045930 Negative regulation of mitotic cell cycle Increases phenotype PMID:24814887
GO:0046466 Membrane lipid catabolic process Increases phenotype PMID:15621696
GO:0051276 Chromosome organization Decreases phenotype PMID:31712135
GO:0051353 Positive regulation of oxidoreductase activity Increases phenotype PMID:33811995
GO:0060278 Regulation of ovulation Affects phenotype PMID:27163632
GO:0061370 Testosterone biosynthetic process Affects phenotype PMID:35487396
GO:0070192 Chromosome organization involved in meiotic cell cycle Decreases phenotype PMID:31712135
GO:0070989 Oxidative demethylation Increases phenotype PMID:8498088
GO:0072593 Reactive oxygen species metabolic process Increases phenotype PMID:24814887
GO:0080182 Histone h3-k4 trimethylation Affects phenotype PMID:29094188
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:23712962
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.