2,2',6,6'-Tetrachlorobisphenol A


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0006171 Camp biosynthetic process Increases phenotype PMID:28858478
GO:0006754 Atp biosynthetic process Affects phenotype PMID:35435491
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:26916392
GO:0008283 Cell population proliferation Affects phenotype PMID:26916392; PMID:28616630
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:38369010
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:32763284; PMID:35734227
GO:0019915 Lipid storage Increases phenotype PMID:32763284
GO:0030335 Positive regulation of cell migration Increases phenotype PMID:36190352
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:31388671
GO:0042127 Regulation of cell population proliferation Affects phenotype PMID:33582643
GO:0044237 Cellular metabolic process Increases phenotype PMID:37992829
GO:0046460 Neutral lipid biosynthetic process Increases phenotype PMID:35734227
GO:0055074 Calcium ion homeostasis Affects phenotype PMID:26916392; PMID:28858478
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:26916392
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:33582643; PMID:38369010
GO:2001025 Positive regulation of response to drug Increases phenotype PMID:35734227
GO:2001170 Negative regulation of atp biosynthetic process Increases phenotype PMID:38369010
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.