Vinclozolin


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001510 Rna methylation Decreases phenotype PMID:31146095
GO:0001541 Ovarian follicle development Decreases phenotype PMID:36642194
GO:0006306 Dna methylation Affects phenotype PMID:30207508
GO:0006355 Regulation of dna-templated transcription Increases phenotype PMID:25853433; PMID:32827888
GO:0006805 Xenobiotic metabolic process Increases phenotype PMID:29162470
GO:0006915 Apoptotic process Increases phenotype PMID:23555832
GO:0007283 Spermatogenesis Decreases phenotype PMID:32827888
GO:0008209 Androgen metabolic process Decreases phenotype PMID:25929820
GO:0008210 Estrogen metabolic process Affects phenotype PMID:36642194
GO:0008283 Cell population proliferation Decreases phenotype PMID:17599374
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:25324206
GO:0008584 Male gonad development Decreases phenotype PMID:34182078
GO:0010424 Dna methylation on cytosine within a cg sequence Affects phenotype PMID:31079544
GO:0030262 Apoptotic nuclear changes Increases phenotype PMID:31152826
GO:0031324 Negative regulation of cellular metabolic process Increases phenotype PMID:35413382
GO:0032502 Developmental process Affects phenotype PMID:34182078
GO:0032776 Dna methylation on cytosine Affects phenotype PMID:31682807
GO:0034587 Pirna processing Increases phenotype PMID:30207508
GO:0040015 Negative regulation of multicellular organism growth Increases phenotype PMID:31682807
GO:0040018 Positive regulation of multicellular organism growth Increases phenotype PMID:29535025
GO:0040029 Epigenetic regulation of gene expression Affects phenotype PMID:26677731; PMID:30207508
GO:0042307 Positive regulation of protein import into nucleus Increases phenotype PMID:27684650
GO:0044030 Regulation of dna methylation Affects phenotype PMID:25853433; PMID:26677731
GO:0044237 Cellular metabolic process Increases phenotype PMID:35595151
GO:0044553 Modulation of biological quality in another organism Affects phenotype PMID:32827888
GO:0046621 Negative regulation of organ growth Increases phenotype PMID:32827888
GO:0048513 Animal organ development Decreases phenotype PMID:34182078
GO:0050916 Sensory perception of sweet taste Affects phenotype PMID:23410115
GO:0060765 Regulation of androgen receptor signaling pathway Affects phenotype PMID:25324206
GO:0070374 Positive regulation of erk1 and erk2 cascade Increases phenotype PMID:27413106
GO:0071578 Zinc ion import across plasma membrane Increases phenotype PMID:31152826
GO:0090030 Regulation of steroid hormone biosynthetic process Affects phenotype PMID:23558297
GO:0090727 Positive regulation of brood size Increases phenotype PMID:29535025
GO:0140042 Lipid droplet formation Increases phenotype PMID:37046073
GO:1900745 Positive regulation of p38mapk cascade Increases phenotype PMID:27413106; PMID:35413382
GO:1990349 Gap junction-mediated intercellular transport Decreases phenotype PMID:27413106; PMID:35413382
GO:2000225 Negative regulation of testosterone biosynthetic process Increases phenotype PMID:32827888
GO:2000845 Positive regulation of testosterone secretion Decreases phenotype PMID:25929820
GO:2000866 Positive regulation of estradiol secretion Increases phenotype PMID:25929820
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.