Bisphenol B


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000737 Dna catabolic process, endonucleolytic Increases phenotype PMID:33392205
GO:0001541 Ovarian follicle development Decreases phenotype PMID:31424294
GO:0001547 Antral ovarian follicle growth Increases phenotype PMID:31424294
GO:0004000 Adenosine deaminase activity Increases phenotype PMID:39577800
GO:0004112 Cyclic-nucleotide phosphodiesterase activity Increases phenotype PMID:39577800
GO:0004784 Superoxide dismutase activity Decreases phenotype PMID:31424294
GO:0006171 Camp biosynthetic process Increases phenotype PMID:28858478
GO:0006629 Lipid metabolic process Affects phenotype PMID:31820560
GO:0006701 Progesterone biosynthetic process Decreases phenotype PMID:31424294
GO:0006874 Cellular calcium ion homeostasis Affects phenotype PMID:32508751
GO:0006915 Apoptotic process Increases phenotype PMID:39577800
GO:0007057 Spindle assembly involved in female meiosis i Affects phenotype PMID:33392205
GO:0007127 Meiosis i Affects phenotype PMID:33392205
GO:0007283 Spermatogenesis Decreases phenotype PMID:29940534
GO:0008202 Steroid metabolic process Affects phenotype PMID:24563381
GO:0008210 Estrogen metabolic process Increases phenotype PMID:24563381
GO:0008283 Cell population proliferation Affects phenotype PMID:24213142; PMID:24213142; PMID:28616630; PMID:37182577; PMID:39577800
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:28591870; PMID:30099086
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:29555536; PMID:32763284
GO:0016042 Lipid catabolic process Increases phenotype PMID:31424294
GO:0016345 Female meiotic chromosome movement towards spindle pole Affects phenotype PMID:33392205
GO:0022402 Cell cycle process Affects phenotype PMID:33940105
GO:0030182 Neuron differentiation Decreases phenotype PMID:39577800
GO:0030283 Testosterone dehydrogenase [nad(p)] activity Decreases phenotype PMID:39313105
GO:0032869 Cellular response to insulin stimulus Affects phenotype PMID:34186270
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:31388671
GO:0034440 Lipid oxidation Increases phenotype PMID:29940534; PMID:39577800
GO:0035937 Estrogen secretion Affects phenotype PMID:37182577
GO:0036124 Histone h3-k9 trimethylation Increases phenotype PMID:33392205
GO:0036343 Psychomotor behavior Affects phenotype PMID:39577800
GO:0040038 Polar body extrusion after meiotic divisions Affects phenotype PMID:33392205
GO:0042403 Thyroid hormone metabolic process Affects phenotype PMID:36881955
GO:0042701 Progesterone secretion Affects phenotype PMID:37182577
GO:0044237 Cellular metabolic process Decreases phenotype PMID:31812737; PMID:33753083
GO:0044319 Wound healing, spreading of cells Increases phenotype PMID:28858478
GO:0045444 Fat cell differentiation Increases phenotype PMID:34186270; PMID:39842701
GO:0045931 Positive regulation of mitotic cell cycle Increases phenotype PMID:32387340
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:39577800
GO:0048143 Astrocyte activation Increases phenotype PMID:39577800
GO:0055074 Calcium ion homeostasis Affects phenotype PMID:28858478
GO:0061370 Testosterone biosynthetic process Increases phenotype PMID:28482050; PMID:31424294; PMID:33753083; PMID:33940105; PMID:37164221
GO:0071929 Alpha-tubulin acetylation Increases phenotype PMID:33392205
GO:0090687 Activation of meiosis i spindle assembly checkpoint Increases phenotype PMID:33392205
GO:0097621 Monoamine oxidase activity Increases phenotype PMID:39577800
GO:0098532 Histone h3-k27 trimethylation Increases phenotype PMID:33392205
GO:0140042 Lipid droplet formation Increases phenotype PMID:32763284
GO:1903046 Meiotic cell cycle process Affects phenotype PMID:33392205
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:31424294
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:29940534
GO:1903709 Uterine gland development Affects phenotype PMID:36881955
GO:1990138 Neuron projection extension Affects phenotype PMID:31812737
GO:1990375 Baculum development Affects phenotype PMID:37164221
GO:2000225 Negative regulation of testosterone biosynthetic process Increases phenotype PMID:29940534
GO:2000469 Negative regulation of peroxidase activity Increases phenotype PMID:29940534
GO:2000844 Negative regulation of testosterone secretion Increases phenotype PMID:29940534
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.