Perfluoro-n-nonanoic acid


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0003016 Respiratory system process Decreases phenotype PMID:30737192
GO:0003094 Glomerular filtration Decreases phenotype PMID:23482063
GO:0003997 Acyl-coa oxidase activity Increases phenotype PMID:8831811
GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity Decreases phenotype PMID:29156323
GO:0004784 Superoxide dismutase activity Decreases phenotype PMID:39933620
GO:0006119 Oxidative phosphorylation Decreases phenotype PMID:39933620
GO:0006629 Lipid metabolic process Affects phenotype PMID:32634666
GO:0006641 Triglyceride metabolic process Affects phenotype PMID:32588087; PMID:38117326
GO:0006694 Steroid biosynthetic process Affects phenotype PMID:33991873
GO:0006954 Inflammatory response Decreases phenotype PMID:32916415
GO:0007605 Sensory perception of sound Affects phenotype PMID:32474307
GO:0007612 Learning Affects phenotype PMID:32521479
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:30294798; PMID:33993001; PMID:33993001; PMID:36069575
GO:0008217 Regulation of blood pressure Affects phenotype PMID:24218149
GO:0008219 Cell death Affects phenotype PMID:26599974; PMID:39933616
GO:0008283 Cell population proliferation Affects phenotype PMID:23539207
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:35337807
GO:0010424 Dna methylation on cytosine within a cg sequence Affects phenotype PMID:33356526; PMID:35266797
GO:0010890 Positive regulation of sequestering of triglyceride Increases phenotype PMID:28049043
GO:0010942 Positive regulation of cell death Increases phenotype PMID:27511595
GO:0015721 Bile acid and bile salt transport Affects phenotype PMID:29112762
GO:0016049 Cell growth Decreases phenotype PMID:30144469
GO:0019216 Regulation of lipid metabolic process Affects phenotype PMID:33483757
GO:0019369 Arachidonic acid metabolic process Affects phenotype PMID:33991873
GO:0030282 Bone mineralization Affects phenotype PMID:26058082; PMID:34585601; PMID:35750749
GO:0030308 Negative regulation of cell growth Increases phenotype PMID:36341878
GO:0032374 Regulation of cholesterol transport Affects phenotype PMID:29112762
GO:0032782 Bile acid secretion Increases phenotype PMID:29112762
GO:0034440 Lipid oxidation Affects phenotype PMID:39933620
GO:0035937 Estrogen secretion Affects phenotype PMID:39933620
GO:0036109 Alpha-linolenic acid metabolic process Affects phenotype PMID:33991873
GO:0036343 Psychomotor behavior Affects phenotype PMID:32272335
GO:0042403 Thyroid hormone metabolic process Increases phenotype PMID:26517287; PMID:33243245
GO:0042593 Glucose homeostasis Affects phenotype PMID:32807188; PMID:33984575
GO:0042632 Cholesterol homeostasis Affects phenotype PMID:26056853; PMID:29112762
GO:0042701 Progesterone secretion Affects phenotype PMID:39933620
GO:0043396 Corticotropin-releasing hormone secretion Increases phenotype PMID:33824413
GO:0043651 Linoleic acid metabolic process Affects phenotype PMID:33991873
GO:0044237 Cellular metabolic process Increases phenotype PMID:35380827; PMID:36326898; PMID:36864359; PMID:38117326; PMID:38549690
GO:0045444 Fat cell differentiation Increases phenotype PMID:34800597; PMID:39111555
GO:0045540 Regulation of cholesterol biosynthetic process Affects phenotype PMID:29112762
GO:0045793 Positive regulation of cell size Increases phenotype PMID:28049043
GO:0046034 Atp metabolic process Affects phenotype PMID:39933620
GO:0046339 Diacylglycerol metabolic process Affects phenotype PMID:33113464
GO:0046890 Regulation of lipid biosynthetic process Affects phenotype PMID:34500360
GO:0048513 Animal organ development Increases phenotype PMID:34500361
GO:0048589 Developmental growth Decreases phenotype PMID:26895313
GO:0050890 Cognition Affects phenotype PMID:32272335
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:39933620
GO:0051882 Mitochondrial depolarization Increases phenotype PMID:39933620
GO:0060443 Mammary gland morphogenesis Decreases phenotype PMID:27511595
GO:0070162 Adiponectin secretion Decreases phenotype PMID:31216000
GO:0070328 Triglyceride homeostasis Affects phenotype PMID:26056853
GO:0070857 Regulation of bile acid biosynthetic process Affects phenotype PMID:29112762
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:39933620
GO:0090206 Negative regulation of cholesterol metabolic process Increases phenotype PMID:26056853
GO:0090209 Negative regulation of triglyceride metabolic process Increases phenotype PMID:26056853
GO:1901164 Negative regulation of trophoblast cell migration Increases phenotype PMID:35548680
GO:1901318 Negative regulation of flagellated sperm motility Affects phenotype PMID:30294798
GO:1901670 Negative regulation of superoxide dismutase activity Increases phenotype PMID:30294798
GO:1902552 Negative regulation of catalase activity Increases phenotype PMID:30294798
GO:1903180 Negative regulation of dopamine biosynthetic process Increases phenotype PMID:34371090
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:36075290
GO:1904253 Positive regulation of bile acid metabolic process Increases phenotype PMID:34627976
GO:1904358 Positive regulation of telomere maintenance via telomere lengthening Increases phenotype PMID:34193151
GO:2000609 Regulation of thyroid hormone generation Affects phenotype PMID:29488882
GO:2000611 Positive regulation of thyroid hormone generation Increases phenotype PMID:31518930
GO:2000614 Positive regulation of thyroid-stimulating hormone secretion Increases phenotype PMID:26517287
GO:2000844 Negative regulation of testosterone secretion Increases phenotype PMID:30294798
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.