| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0002523 | Leukocyte migration involved in inflammatory response | Increases phenotype | PMID:32967526; PMID:39368565 |
| GO:0004602 | Glutathione peroxidase activity | Decreases phenotype | PMID:32967526 |
| GO:0004784 | Superoxide dismutase activity | Decreases phenotype | PMID:32967526 |
| GO:0006602 | Creatinine catabolic process | Decreases phenotype | PMID:27363640 |
| GO:0006749 | Glutathione metabolic process | Affects phenotype | PMID:24316378 |
| GO:0007283 | Spermatogenesis | Decreases phenotype | PMID:24316378 |
| GO:0008283 | Cell population proliferation | Increases phenotype | PMID:32967526 |
| GO:0010424 | Dna methylation on cytosine within a cg sequence | Affects phenotype | PMID:27415467 |
| GO:0030199 | Collagen fibril organization | Increases phenotype | PMID:32967526 |
| GO:0030850 | Prostate gland development | Decreases phenotype | PMID:39368565 |
| GO:0032930 | Positive regulation of superoxide anion generation | Increases phenotype | PMID:27363640 |
| GO:0034440 | Lipid oxidation | Increases phenotype | PMID:24316378; PMID:27363640; PMID:32967526 |
| GO:0035264 | Multicellular organism growth | Affects phenotype | PMID:35026373 |
| GO:0035815 | Positive regulation of renal sodium excretion | Increases phenotype | PMID:27363640 |
| GO:0043065 | Positive regulation of apoptotic process | Increases phenotype | PMID:24316378 |
| GO:0045454 | Cell redox homeostasis | Decreases phenotype | PMID:24316378 |
| GO:0046415 | Urate metabolic process | Decreases phenotype | PMID:27363640 |
| GO:0046622 | Positive regulation of organ growth | Increases phenotype | PMID:27830003 |
| GO:0055075 | Potassium ion homeostasis | Decreases phenotype | PMID:27363640 |
| GO:0060179 | Male mating behavior | Increases phenotype | PMID:35026373 |
| GO:0061370 | Testosterone biosynthetic process | Decreases phenotype | PMID:24316378 |
| GO:0090327 | Negative regulation of locomotion involved in locomotory behavior | Increases phenotype | PMID:35026373 |
| GO:1901671 | Positive regulation of superoxide dismutase activity | Decreases phenotype | PMID:24316378 |
| GO:1901687 | Glutathione derivative biosynthetic process | Decreases phenotype | PMID:24316378 |
| GO:1902437 | Positive regulation of male mating behavior | Increases phenotype | PMID:35026373 |
| GO:2000845 | Positive regulation of testosterone secretion | Decreases phenotype | PMID:24316378 |
| GO:2001025 | Positive regulation of response to drug | Decreases phenotype | PMID:27363640 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.