Triclocarban


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0006094 Gluconeogenesis Decreases phenotype PMID:31576746
GO:0006633 Fatty acid biosynthetic process Increases phenotype PMID:31576746
GO:0006636 Unsaturated fatty acid biosynthetic process Increases phenotype PMID:31576746
GO:0006646 Phosphatidylethanolamine biosynthetic process Decreases phenotype PMID:31576746
GO:0006686 Sphingomyelin biosynthetic process Decreases phenotype PMID:31576746
GO:0008283 Cell population proliferation Increases phenotype PMID:24740835; PMID:37385329
GO:0008610 Lipid biosynthetic process Increases phenotype PMID:31576746
GO:0008652 Amino acid biosynthetic process Affects phenotype PMID:31576746
GO:0008654 Phospholipid biosynthetic process Affects phenotype PMID:31576746
GO:0010942 Positive regulation of cell death Increases phenotype PMID:25449125; PMID:28940058
GO:0019249 Lactate biosynthetic process Increases phenotype PMID:31576746
GO:0019432 Triglyceride biosynthetic process Increases phenotype PMID:31576746
GO:0022900 Electron transport chain Decreases phenotype PMID:38631510
GO:0031324 Negative regulation of cellular metabolic process Increases phenotype PMID:35413382
GO:0031589 Cell-substrate adhesion Increases phenotype PMID:34801682
GO:0042431 Indole metabolic process Affects phenotype PMID:37385329
GO:0046322 Negative regulation of fatty acid oxidation Increases phenotype PMID:38631510
GO:0046459 Short-chain fatty acid metabolic process Decreases phenotype PMID:37385329
GO:0046513 Ceramide biosynthetic process Affects phenotype PMID:31576746
GO:0070373 Negative regulation of erk1 and erk2 cascade Increases phenotype PMID:35413382
GO:0072676 Lymphocyte migration Increases phenotype PMID:37385329
GO:0086003 Cardiac muscle cell contraction Increases phenotype PMID:28940058
GO:0140042 Lipid droplet formation Increases phenotype PMID:31576746; PMID:38631510
GO:1900409 Positive regulation of cellular response to oxidative stress Increases phenotype PMID:38631510
GO:1903578 Regulation of atp metabolic process Affects phenotype PMID:28940058
GO:1903753 Negative regulation of p38mapk cascade Increases phenotype PMID:35413382
GO:1903893 Positive regulation of atf6-mediated unfolded protein response Increases phenotype PMID:30592132
GO:1903899 Positive regulation of perk-mediated unfolded protein response Increases phenotype PMID:30592132
GO:1903966 Monounsaturated fatty acid biosynthetic process Increases phenotype PMID:31576746
GO:1904203 Positive regulation of iodide transport Increases phenotype PMID:32065294
GO:1904214 Positive regulation of iodide transmembrane transport Decreases phenotype PMID:26827900
GO:1990349 Gap junction-mediated intercellular transport Decreases phenotype PMID:35413382
GO:2000611 Positive regulation of thyroid hormone generation Increases phenotype PMID:30940137
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.