Triphenyl phosphate


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001503 Ossification Decreases phenotype PMID:30561715
GO:0001655 Urogenital system development Affects phenotype PMID:32360330
GO:0001958 Endochondral ossification Decreases phenotype PMID:33367866
GO:0004035 Alkaline phosphatase activity Decreases phenotype PMID:25062436
GO:0004104 Cholinesterase activity Decreases phenotype PMID:30589522
GO:0004364 Glutathione transferase activity Decreases phenotype PMID:26183808
GO:0004602 Glutathione peroxidase activity Increases phenotype PMID:26183808
GO:0004784 Superoxide dismutase activity Increases phenotype PMID:26183808
GO:0005739 Mitochondrion Increases phenotype PMID:38518089
GO:0005764 Lysosome Affects phenotype PMID:38518089; PMID:38603619
GO:0006006 Glucose metabolic process Affects phenotype PMID:37042841
GO:0006629 Lipid metabolic process Affects phenotype PMID:24597639; PMID:36563926; PMID:36563926; PMID:38450882
GO:0006641 Triglyceride metabolic process Affects phenotype PMID:36563926
GO:0006651 Diacylglycerol biosynthetic process Increases phenotype PMID:24597639
GO:0006672 Ceramide metabolic process Affects phenotype PMID:38048832
GO:0006695 Cholesterol biosynthetic process Affects phenotype PMID:31724879
GO:0006701 Progesterone biosynthetic process Increases phenotype PMID:28282128
GO:0006749 Glutathione metabolic process Affects phenotype PMID:26049154
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:26183808
GO:0006915 Apoptotic process Increases phenotype PMID:37149271
GO:0006954 Inflammatory response Increases phenotype PMID:36563926
GO:0007005 Mitochondrion organization Affects phenotype PMID:37149271
GO:0007040 Lysosome organization Decreases phenotype PMID:35135005
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:36563926
GO:0008283 Cell population proliferation Affects phenotype PMID:26183808; PMID:36563926
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:26979758; PMID:37827210
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:30974155
GO:0008923 Lysine decarboxylase activity Decreases phenotype PMID:25264276
GO:0009060 Aerobic respiration Decreases phenotype PMID:30966736
GO:0010884 Positive regulation of lipid storage Increases phenotype PMID:28163246; PMID:28934090
GO:0010942 Positive regulation of cell death Increases phenotype PMID:26049154
GO:0010975 Regulation of neuron projection development Affects phenotype PMID:32243540
GO:0015908 Fatty acid transport Affects phenotype PMID:34323617
GO:0016042 Lipid catabolic process Increases phenotype PMID:26183808
GO:0016477 Cell migration Decreases phenotype PMID:33969458
GO:0019432 Triglyceride biosynthetic process Increases phenotype PMID:24597639; PMID:31724879
GO:0030335 Positive regulation of cell migration Increases phenotype PMID:35776891
GO:0030539 Male genitalia development Affects phenotype PMID:33280148
GO:0032125 Micronucleus organization Increases phenotype PMID:36372259
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:26979758
GO:0033344 Cholesterol efflux Increases phenotype PMID:31724879
GO:0035633 Maintenance of blood-brain barrier Decreases phenotype PMID:35752650
GO:0035932 Aldosterone secretion Increases phenotype PMID:38450882
GO:0035933 Glucocorticoid secretion Increases phenotype PMID:38450882
GO:0035936 Testosterone secretion Increases phenotype PMID:38450882
GO:0035937 Estrogen secretion Increases phenotype PMID:38450882
GO:0040018 Positive regulation of multicellular organism growth Increases phenotype PMID:32360330
GO:0042632 Cholesterol homeostasis Decreases phenotype PMID:30589522; PMID:30966736
GO:0042701 Progesterone secretion Increases phenotype PMID:38450882
GO:0044237 Cellular metabolic process Decreases phenotype PMID:33078273; PMID:37149271
GO:0044242 Cellular lipid catabolic process Increases phenotype PMID:28163246
GO:0044255 Cellular lipid metabolic process Affects phenotype PMID:34323617
GO:0045444 Fat cell differentiation Increases phenotype PMID:25062436; PMID:28437481; PMID:32473317
GO:0045600 Positive regulation of fat cell differentiation Increases phenotype PMID:28163246
GO:0046034 Atp metabolic process Affects phenotype PMID:30966736; PMID:37149271
GO:0046326 Positive regulation of glucose import Increases phenotype PMID:28163246
GO:0046470 Phosphatidylcholine metabolic process Affects phenotype PMID:38048832
GO:0046622 Positive regulation of organ growth Increases phenotype PMID:29316351; PMID:30589522
GO:0048146 Positive regulation of fibroblast proliferation Increases phenotype PMID:28163246
GO:0048709 Oligodendrocyte differentiation Decreases phenotype PMID:33969458
GO:0051216 Cartilage development Decreases phenotype PMID:30561715
GO:0051346 Negative regulation of hydrolase activity Affects phenotype PMID:30589522
GO:0051882 Mitochondrial depolarization Increases phenotype PMID:37149271
GO:0052689 Carboxylic ester hydrolase activity Decreases phenotype PMID:32511959
GO:0061370 Testosterone biosynthetic process Decreases phenotype PMID:26183808
GO:0070050 Neuron cellular homeostasis Decreases phenotype PMID:37120036
GO:0070091 Glucagon secretion Affects phenotype PMID:36613676
GO:0070254 Mucus secretion Increases phenotype PMID:36563926
GO:0070265 Necrotic cell death Increases phenotype PMID:36563926
GO:0070328 Triglyceride homeostasis Decreases phenotype PMID:30966736
GO:0072593 Reactive oxygen species metabolic process Affects phenotype PMID:37149271; PMID:38518089
GO:0090077 Foam cell differentiation Increases phenotype PMID:31724879
GO:0090357 Regulation of tryptophan metabolic process Affects phenotype PMID:32243540
GO:0097150 Neuronal stem cell population maintenance Decreases phenotype PMID:35752650
GO:0140042 Lipid droplet formation Increases phenotype PMID:28437481; PMID:28934090; PMID:35135005; PMID:36563926; PMID:38450882; PMID:38603619
GO:1901142 Insulin metabolic process Affects phenotype PMID:37042841
GO:1901687 Glutathione derivative biosynthetic process Increases phenotype PMID:26049154
GO:1903078 Positive regulation of protein localization to plasma membrane Increases phenotype PMID:28163246
GO:1903284 Positive regulation of glutathione peroxidase activity Increases phenotype PMID:26049154
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:24395120
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:35135005
GO:1904179 Positive regulation of adipose tissue development Increases phenotype PMID:28934090
GO:2000610 Negative regulation of thyroid hormone generation Increases phenotype PMID:30589522
GO:2000845 Positive regulation of testosterone secretion Decreases phenotype PMID:26049154
GO:2000866 Positive regulation of estradiol secretion Increases phenotype PMID:38603619
GO:2000872 Positive regulation of progesterone secretion Increases phenotype PMID:38603619
GO:2000978 Negative regulation of forebrain neuron differentiation Increases phenotype PMID:35752650
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.