Carbendazim


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000086 G2/m transition of mitotic cell cycle Increases phenotype PMID:30851412
GO:0000212 Meiotic spindle organization Affects phenotype PMID:37506866
GO:0002523 Leukocyte migration involved in inflammatory response Increases phenotype PMID:35513110
GO:0004364 Glutathione transferase activity Affects phenotype PMID:27268782; PMID:33217513
GO:0004602 Glutathione peroxidase activity Affects phenotype PMID:33217513; PMID:33965443
GO:0004784 Superoxide dismutase activity Decreases phenotype PMID:33965443
GO:0006308 Dna catabolic process Increases phenotype PMID:35513110
GO:0006749 Glutathione metabolic process Affects phenotype PMID:27268782; PMID:33217513; PMID:33965443; PMID:35513110
GO:0006915 Apoptotic process Increases phenotype PMID:27286660; PMID:35437878; PMID:35513110
GO:0006954 Inflammatory response Increases phenotype PMID:35437878
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:33217513
GO:0007033 Vacuole organization Increases phenotype PMID:32418910
GO:0007133 Meiotic anaphase i Affects phenotype PMID:37506866
GO:0007134 Meiotic telophase i Affects phenotype PMID:37506866
GO:0007144 Female meiosis i Affects phenotype PMID:37506866
GO:0007283 Spermatogenesis Decreases phenotype PMID:15141104; PMID:33965443
GO:0007284 Spermatogonial cell division Decreases phenotype PMID:28576679
GO:0007285 Primary spermatocyte growth Affects phenotype PMID:28576679
GO:0007286 Spermatid development Increases phenotype PMID:27466211; PMID:28576679
GO:0008219 Cell death Increases phenotype PMID:32418910
GO:0008283 Cell population proliferation Decreases phenotype PMID:19001156
GO:0009566 Fertilization Affects phenotype PMID:37506866
GO:0010942 Positive regulation of cell death Increases phenotype PMID:20654549
GO:0010972 Negative regulation of g2/m transition of mitotic cell cycle Increases phenotype PMID:25543211
GO:0016042 Lipid catabolic process Increases phenotype PMID:33217513; PMID:33965443; PMID:35513110; PMID:35705592
GO:0019216 Regulation of lipid metabolic process Affects phenotype PMID:26071454
GO:0019627 Urea metabolic process Affects phenotype PMID:27268782
GO:0022900 Electron transport chain Decreases phenotype PMID:30851412
GO:0030199 Collagen fibril organization Increases phenotype PMID:35437878
GO:0034440 Lipid oxidation Affects phenotype PMID:27268782
GO:0035640 Exploration behavior Decreases phenotype PMID:35513110
GO:0036124 Histone h3-k9 trimethylation Increases phenotype PMID:37506866
GO:0036269 Swimming behavior Affects phenotype PMID:35513110
GO:0040038 Polar body extrusion after meiotic divisions Decreases phenotype PMID:37506866
GO:0042403 Thyroid hormone metabolic process Affects phenotype PMID:33965443
GO:0042593 Glucose homeostasis Affects phenotype PMID:30496565
GO:0042743 Hydrogen peroxide metabolic process Affects phenotype PMID:27268782
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:25530041
GO:0044237 Cellular metabolic process Decreases phenotype PMID:30851412; PMID:33965443
GO:0045023 G0 to g1 transition Decreases phenotype PMID:30851412
GO:0045454 Cell redox homeostasis Decreases phenotype PMID:35705592
GO:0045930 Negative regulation of mitotic cell cycle Affects phenotype PMID:27286660; PMID:30851412
GO:0045931 Positive regulation of mitotic cell cycle Decreases phenotype PMID:25530041
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:27268782
GO:0046449 Creatinine metabolic process Affects phenotype PMID:27268782
GO:0046483 Heterocycle metabolic process Affects phenotype PMID:38734222
GO:0048137 Spermatocyte division Decreases phenotype PMID:28576679
GO:0048874 Host-mediated regulation of intestinal microbiota composition Affects phenotype PMID:30496565
GO:0051307 Meiotic chromosome separation Affects phenotype PMID:37506866
GO:0061370 Testosterone biosynthetic process Affects phenotype PMID:33965443
GO:0070265 Necrotic cell death Increases phenotype PMID:35437878; PMID:35513110
GO:0070328 Triglyceride homeostasis Affects phenotype PMID:30496565
GO:0070734 Histone h3-k27 methylation Increases phenotype PMID:37506866
GO:0070994 Detection of oxidative stress Increases phenotype PMID:27286660; PMID:35437878; PMID:35513110
GO:0071929 Alpha-tubulin acetylation Increases phenotype PMID:37506866
GO:0090207 Regulation of triglyceride metabolic process Affects phenotype PMID:30496565
GO:0097412 Hyaline inclusion Increases phenotype PMID:35437878
GO:0097722 Sperm motility Decreases phenotype PMID:33965443
GO:0098532 Histone h3-k27 trimethylation Increases phenotype PMID:37506866
GO:0140042 Lipid droplet formation Increases phenotype PMID:35437878
GO:1901165 Positive regulation of trophoblast cell migration Decreases phenotype PMID:25530041
GO:1901670 Negative regulation of superoxide dismutase activity Increases phenotype PMID:27268782
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:30851412
GO:1903537 Meiotic cell cycle process involved in oocyte maturation Affects phenotype PMID:37506866
GO:1904729 Regulation of intestinal lipid absorption Affects phenotype PMID:30496565
GO:2000255 Negative regulation of male germ cell proliferation Increases phenotype PMID:28576679
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.