Daidzein


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0001516 Prostaglandin biosynthetic process Increases phenotype PMID:21341175
GO:0004035 Alkaline phosphatase activity Increases phenotype PMID:35986755
GO:0004784 Superoxide dismutase activity Decreases phenotype PMID:23135684; PMID:39425453
GO:0005975 Carbohydrate metabolic process Affects phenotype PMID:39954026
GO:0006020 Inositol metabolic process Affects phenotype PMID:39954026
GO:0006071 Glycerol metabolic process Affects phenotype PMID:39954026
GO:0006309 Apoptotic dna fragmentation Increases phenotype PMID:12791511
GO:0006520 Amino acid metabolic process Affects phenotype PMID:39954026
GO:0006629 Lipid metabolic process Affects phenotype PMID:39954026
GO:0006631 Fatty acid metabolic process Affects phenotype PMID:39954026
GO:0006711 Estrogen catabolic process Increases phenotype PMID:28985473
GO:0006743 Ubiquinone metabolic process Affects phenotype PMID:39954026
GO:0006749 Glutathione metabolic process Affects phenotype PMID:39425453
GO:0006750 Glutathione biosynthetic process Decreases phenotype PMID:23135684
GO:0006809 Nitric oxide biosynthetic process Increases phenotype PMID:23135684
GO:0006915 Apoptotic process Increases phenotype PMID:12791511; PMID:39425453
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:39954026
GO:0008283 Cell population proliferation Increases phenotype PMID:12791511; PMID:24062438; PMID:24213142; PMID:24213142; PMID:28855101; PMID:32926937
GO:0008284 Positive regulation of cell population proliferation Increases phenotype PMID:25661160; PMID:28396216
GO:0008285 Negative regulation of cell population proliferation Affects phenotype PMID:23526725
GO:0019858 Cytosine metabolic process Affects phenotype PMID:39954026
GO:0019860 Uracil metabolic process Affects phenotype PMID:39954026
GO:0030036 Actin cytoskeleton organization Affects phenotype PMID:32963737
GO:0031941 Filamentous actin Affects phenotype PMID:32963737
GO:0032148 Activation of protein kinase b activity Decreases phenotype PMID:29217487
GO:0033148 Positive regulation of intracellular estrogen receptor signaling pathway Increases phenotype PMID:25661160; PMID:28396216
GO:0034275 Kynurenic acid metabolic process Affects phenotype PMID:39954026
GO:0034614 Cellular response to reactive oxygen species Decreases phenotype PMID:22683914
GO:0036474 Cell death in response to hydrogen peroxide Affects phenotype PMID:23526725
GO:0042360 Vitamin e metabolic process Affects phenotype PMID:39954026
GO:0042414 Epinephrine metabolic process Affects phenotype PMID:39954026
GO:0042428 Serotonin metabolic process Affects phenotype PMID:39954026
GO:0042431 Indole metabolic process Affects phenotype PMID:39954026
GO:0042445 Hormone metabolic process Affects phenotype PMID:39954026
GO:0043277 Apoptotic cell clearance Increases phenotype PMID:24859791
GO:0044237 Cellular metabolic process Affects phenotype PMID:35986755; PMID:38969211
GO:0045444 Fat cell differentiation Increases phenotype PMID:30920877
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:39425453
GO:0046466 Membrane lipid catabolic process Affects phenotype PMID:39425453
GO:0046961 Proton-transporting atpase activity, rotational mechanism Decreases phenotype PMID:10882397
GO:0051091 Positive regulation of dna-binding transcription factor activity Increases phenotype PMID:29688519
GO:0051092 Positive regulation of nf-kappab transcription factor activity Decreases phenotype PMID:22683914
GO:0051881 Regulation of mitochondrial membrane potential Affects phenotype PMID:24859791
GO:0060209 Estrus Affects phenotype PMID:28964809
GO:0060210 Metestrus Affects phenotype PMID:28964809
GO:0140042 Lipid droplet formation Increases phenotype PMID:30920877
GO:1901224 Positive regulation of nik/nf-kappab signaling Decreases phenotype PMID:22683914
GO:1905603 Regulation of blood-brain barrier permeability Affects phenotype PMID:39425453
GO:2000866 Positive regulation of estradiol secretion Decreases phenotype PMID:28964809
GO:2000872 Positive regulation of progesterone secretion Decreases phenotype PMID:28964809
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.