1,3-Butadiene


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0004129 Cytochrome-c oxidase activity Decreases phenotype PMID:28082109
GO:0005975 Carbohydrate metabolic process Affects phenotype PMID:34648870
GO:0006096 Glycolytic process Affects phenotype PMID:34648870
GO:0006099 Tricarboxylic acid cycle Affects phenotype PMID:34648870
GO:0006304 Dna modification Increases phenotype PMID:29038090; PMID:30990016; PMID:30990016
GO:0006338 Chromatin remodeling Increases phenotype PMID:29038090
GO:0006631 Fatty acid metabolic process Affects phenotype PMID:34648870
GO:0006687 Glycosphingolipid metabolic process Affects phenotype PMID:34648870
GO:0008137 Nadh dehydrogenase (ubiquinone) activity Decreases phenotype PMID:28082109
GO:0008177 Succinate dehydrogenase (ubiquinone) activity Decreases phenotype PMID:28082109
GO:0008207 C21-steroid hormone metabolic process Affects phenotype PMID:34648870
GO:0008652 Amino acid biosynthetic process Affects phenotype PMID:34648870
GO:0016125 Sterol metabolic process Affects phenotype PMID:34648870
GO:0019858 Cytosine metabolic process Affects phenotype PMID:34648870
GO:0019860 Uracil metabolic process Affects phenotype PMID:34648870
GO:0034773 Histone h4-k20 trimethylation Increases phenotype PMID:25237060; PMID:30552462; PMID:30552462; PMID:30990016
GO:0036124 Histone h3-k9 trimethylation Increases phenotype PMID:30552462
GO:0070085 Glycosylation Affects phenotype PMID:34648870
GO:0097043 Histone h3-k56 acetylation Decreases phenotype PMID:25237060
GO:0098532 Histone h3-k27 trimethylation Increases phenotype PMID:30552462
GO:1900113 Negative regulation of histone h3-k9 trimethylation Increases phenotype PMID:30990016
GO:1900114 Positive regulation of histone h3-k9 trimethylation Increases phenotype PMID:25237060
GO:1901535 Regulation of dna demethylation Affects phenotype PMID:25237060
GO:1901675 Negative regulation of histone h3-k27 acetylation Increases phenotype PMID:30990016
GO:1901676 Positive regulation of histone h3-k27 acetylation Increases phenotype PMID:25237060
GO:1902466 Positive regulation of histone h3-k27 trimethylation Increases phenotype PMID:25237060
GO:2000619 Negative regulation of histone h4-k16 acetylation Increases phenotype PMID:25237060
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.