| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0006006 | Glucose metabolic process | Affects phenotype | PMID:33246813 |
| GO:0006090 | Pyruvate metabolic process | Affects phenotype | PMID:33246813 |
| GO:0006631 | Fatty acid metabolic process | Affects phenotype | PMID:33246813 |
| GO:0006641 | Triglyceride metabolic process | Affects phenotype | PMID:33246813 |
| GO:0006915 | Apoptotic process | Increases phenotype | PMID:34549778 |
| GO:0006974 | Cellular response to dna damage stimulus | Increases phenotype | PMID:19591892 |
| GO:0007224 | Smoothened signaling pathway | Decreases phenotype | PMID:31652400 |
| GO:0008284 | Positive regulation of cell population proliferation | Decreases phenotype | PMID:28426875 |
| GO:0008285 | Negative regulation of cell population proliferation | Increases phenotype | PMID:29555536 |
| GO:0009437 | Carnitine metabolic process | Affects phenotype | PMID:33246813 |
| GO:0043065 | Positive regulation of apoptotic process | Increases phenotype | PMID:30586609 |
| GO:0045617 | Negative regulation of keratinocyte differentiation | Increases phenotype | PMID:32289622 |
| GO:0046621 | Negative regulation of organ growth | Increases phenotype | PMID:30586609 |
| GO:0048160 | Primary follicle stage | Increases phenotype | PMID:30586609 |
| GO:0051548 | Negative regulation of keratinocyte migration | Increases phenotype | PMID:32289622 |
| GO:0051881 | Regulation of mitochondrial membrane potential | Affects phenotype | PMID:34549778 |
| GO:0072537 | Fibroblast activation | Increases phenotype | PMID:32289622 |
| GO:0072593 | Reactive oxygen species metabolic process | Affects phenotype | PMID:34549778 |
| GO:1905071 | Tight junction disassembly | Increases phenotype | PMID:34549778 |
| GO:2000355 | Negative regulation of ovarian follicle development | Increases phenotype | PMID:30586609 |
| GO:2000865 | Negative regulation of estradiol secretion | Increases phenotype | PMID:30586609 |
| GO:2000871 | Negative regulation of progesterone secretion | Increases phenotype | PMID:30586609 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.