Triphenyltin hydroxide


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0002156 Negative regulation of thyroid hormone mediated signaling pathway Increases phenotype PMID:31476497
GO:0002157 Positive regulation of thyroid hormone mediated signaling pathway Increases phenotype PMID:31476497
GO:0003712 Transcription coregulator activity Increases phenotype PMID:35483669
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:19591892
GO:0007224 Smoothened signaling pathway Decreases phenotype PMID:31652400
GO:0008283 Cell population proliferation Decreases phenotype PMID:28709983
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:35483669
GO:0016043 Cellular component organization Affects phenotype PMID:35483669
GO:0016505 Peptidase activator activity involved in apoptotic process Increases phenotype PMID:28709983
GO:0044237 Cellular metabolic process Decreases phenotype PMID:33929904
GO:0045444 Fat cell differentiation Increases phenotype PMID:32473317
GO:0048384 Retinoic acid receptor signaling pathway Decreases phenotype PMID:31652400
GO:0048386 Positive regulation of retinoic acid receptor signaling pathway Increases phenotype PMID:35483669
GO:0060070 Canonical wnt signaling pathway Decreases phenotype PMID:31652400
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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.