Hydrogen Peroxide


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000045 Autophagosome assembly Increases phenotype PMID:31332898
GO:0000082 G1/s transition of mitotic cell cycle Decreases phenotype PMID:18957176
GO:0000104 Succinate dehydrogenase activity Decreases phenotype PMID:24700636
GO:0000165 Mapk cascade Increases phenotype PMID:17640472; PMID:18204935
GO:0000226 Microtubule cytoskeleton organization Increases phenotype PMID:21658250
GO:0000266 Mitochondrial fission Increases phenotype PMID:34971761
GO:0000737 Dna catabolic process, endonucleolytic Increases phenotype PMID:14696671; PMID:24925361; PMID:28703385; PMID:32312157; PMID:36932276; PMID:35778544; PMID:36932276
GO:0000910 Cytokinesis Decreases phenotype PMID:28343997
GO:0001503 Ossification Decreases phenotype PMID:39743035
GO:0001649 Osteoblast differentiation Decreases phenotype PMID:26482937
GO:0001836 Release of cytochrome c from mitochondria Increases phenotype PMID:14505808; PMID:16362428; PMID:20433247; PMID:26766292; PMID:29902531; PMID:31306736
GO:0001932 Regulation of protein phosphorylation Affects phenotype PMID:31494107
GO:0002076 Osteoblast development Increases phenotype PMID:27028516
GO:0003777 Microtubule motor activity Increases phenotype PMID:24912985
GO:0003887 Dna-directed dna polymerase activity Increases phenotype PMID:29185360
GO:0003994 Aconitate hydratase activity Decreases phenotype PMID:31306736
GO:0004035 Alkaline phosphatase activity Decreases phenotype PMID:26482937; PMID:31194955
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity Increases phenotype PMID:29992723
GO:0004129 Cytochrome-c oxidase activity Decreases phenotype PMID:22274401; PMID:30316844
GO:0004177 Aminopeptidase activity Decreases phenotype PMID:34225579
GO:0004197 Cysteine-type endopeptidase activity Increases phenotype PMID:30104959; PMID:34077701
GO:0004457 Lactate dehydrogenase activity Affects phenotype PMID:24925361; PMID:34971761; PMID:36058301; PMID:37648050; PMID:38574953
GO:0004602 Glutathione peroxidase activity Affects phenotype PMID:25005833; PMID:25005833; PMID:25108166; PMID:25108166; PMID:28285367; PMID:29185360; PMID:30104959; PMID:32954801; PMID:36058301; PMID:38574953
GO:0004679 Amp-activated protein kinase activity Decreases phenotype PMID:29499335
GO:0004784 Superoxide dismutase activity Increases phenotype PMID:22633977; PMID:23329528; PMID:23329528; PMID:37648050; PMID:25065601; PMID:26339600; PMID:26422756; PMID:26766292; PMID:29185360; PMID:29274434; PMID:29274434; PMID:31157476; PMID:29687528; PMID:29992723; PMID:31157476; PMID:31696622; PMID:38053484; PMID:32954801; PMID:33754447; PMID:36058301; PMID:36880193; PMID:37648050; PMID:38053484; PMID:38555047; PMID:38574953
GO:0005757 Mitochondrial permeability transition pore complex Increases phenotype PMID:33662508
GO:0005776 Autophagosome Increases phenotype PMID:24912985
GO:0005839 Proteasome core complex Increases phenotype PMID:22308036
GO:0005975 Carbohydrate metabolic process Affects phenotype PMID:35227738
GO:0006122 Mitochondrial electron transport, ubiquinol to cytochrome c Decreases phenotype PMID:33290831
GO:0006123 Mitochondrial electron transport, cytochrome c to oxygen Decreases phenotype PMID:25242411
GO:0006167 Amp biosynthetic process Increases phenotype PMID:29992723
GO:0006172 Adp biosynthetic process Increases phenotype PMID:29992723
GO:0006221 Pyrimidine nucleotide biosynthetic process Increases phenotype PMID:27119504
GO:0006259 Dna metabolic process Increases phenotype PMID:24437944; PMID:25781201
GO:0006260 Dna replication Decreases phenotype PMID:1323425
GO:0006284 Base-excision repair Decreases phenotype PMID:25030372
GO:0006298 Mismatch repair Increases phenotype PMID:31294882
GO:0006304 Dna modification Increases phenotype PMID:24925361; PMID:25030372; PMID:28285367; PMID:29289706
GO:0006306 Dna methylation Increases phenotype PMID:29854080
GO:0006308 Dna catabolic process Increases phenotype PMID:24075811; PMID:34196753
GO:0006309 Apoptotic dna fragmentation Increases phenotype PMID:10469363; PMID:12414117; PMID:14505808; PMID:15683462; PMID:15909127; PMID:16100903; PMID:16647178; PMID:16827136; PMID:18082333; PMID:19070971; PMID:21431366; PMID:9184692
GO:0006338 Chromatin remodeling Increases phenotype PMID:26766292
GO:0006355 Regulation of dna-templated transcription Increases phenotype PMID:31162603
GO:0006497 Protein lipidation Increases phenotype PMID:34826546
GO:0006508 Proteolysis Increases phenotype PMID:22308036
GO:0006525 Arginine metabolic process Affects phenotype PMID:35227738
GO:0006556 S-adenosylmethionine biosynthetic process Increases phenotype PMID:27119504
GO:0006606 Protein import into nucleus Increases phenotype PMID:26059411; PMID:26447207; PMID:34077701
GO:0006629 Lipid metabolic process Affects phenotype PMID:35227738
GO:0006641 Triglyceride metabolic process Affects phenotype PMID:29463041
GO:0006693 Prostaglandin metabolic process Affects phenotype PMID:28285367
GO:0006695 Cholesterol biosynthetic process Increases phenotype PMID:29499335
GO:0006749 Glutathione metabolic process Increases phenotype PMID:15228596; PMID:22495766; PMID:24276018; PMID:24437944; PMID:25371773; PMID:26286524; PMID:26286524; PMID:34971761; PMID:27624276; PMID:28163957; PMID:28213291; PMID:28285367; PMID:28754375; PMID:30388846; PMID:31935365; PMID:32679257; PMID:32980322; PMID:34228970; PMID:34499403; PMID:34655286; PMID:34971761; PMID:38555047; PMID:39743035
GO:0006750 Glutathione biosynthetic process Increases phenotype PMID:19723100; PMID:23329528; PMID:23873220; PMID:24590062; PMID:25005833; PMID:25005833; PMID:25108166; PMID:25108166; PMID:26339600; PMID:26419736; PMID:27119504; PMID:27939242; PMID:29274434; PMID:29499335; PMID:29687528; PMID:29992723; PMID:30461186; PMID:31157476; PMID:31226288
GO:0006754 Atp biosynthetic process Decreases phenotype PMID:20616036; PMID:24700636; PMID:29061316; PMID:29992723; PMID:30316844; PMID:31306736
GO:0006776 Vitamin a metabolic process Affects phenotype PMID:28285367
GO:0006809 Nitric oxide biosynthetic process Increases phenotype PMID:20361964; PMID:26766292; PMID:29992723; PMID:31306736
GO:0006874 Cellular calcium ion homeostasis Affects phenotype PMID:30316844; PMID:33309544; PMID:35395232
GO:0006882 Cellular zinc ion homeostasis Decreases phenotype PMID:30229906
GO:0006900 Vesicle budding from membrane Increases phenotype PMID:20946910
GO:0006914 Autophagy Increases phenotype PMID:20307493; PMID:34302491
GO:0006915 Apoptotic process Increases phenotype PMID:10469363; PMID:10486581; PMID:10843682; PMID:10843682; PMID:12642403; PMID:10880836; PMID:10880836; PMID:17645693; PMID:10891466; PMID:11114198; PMID:11132921; PMID:11132921; PMID:12642403; PMID:11306433; PMID:22138401; PMID:11329530; PMID:12177198; PMID:12200813; PMID:12414117; PMID:12414117; PMID:12642403; PMID:17640472; PMID:23189969; PMID:30104959; PMID:34121490; PMID:34971761; PMID:12511591; PMID:12623783; PMID:12642403; PMID:12646174; PMID:12684028; PMID:14696671; PMID:14753751; PMID:15064094; PMID:15081873; PMID:15135655; PMID:15142122; PMID:15380679; PMID:15528046; PMID:15683462; PMID:15683462; PMID:16442562; PMID:15867141; PMID:15909127; PMID:16213648; PMID:16249675; PMID:16442562; PMID:16510162; PMID:17291526; PMID:17498692; PMID:17574045; PMID:17640472; PMID:17645693; PMID:18840609; PMID:19146853; PMID:19703415; PMID:19780897; PMID:19885844; PMID:19961753; PMID:20335659; PMID:20361964; PMID:20594614; PMID:29061316; PMID:31173752; PMID:31638783; PMID:20674559; PMID:21431366; PMID:22138401; PMID:23189969; PMID:23329528; PMID:23329528; PMID:27451028; PMID:28214884; PMID:37648050; PMID:24040102; PMID:24067374; PMID:24239781; PMID:25108166; PMID:25280774; PMID:25280774; PMID:36807289; PMID:25280774; PMID:36807289; PMID:37009741; PMID:25673179; PMID:25972194; PMID:26419736; PMID:26422756; PMID:26447207; PMID:26519223; PMID:27057282; PMID:27180204; PMID:27430346; PMID:27451028; PMID:27525270; PMID:28214884; PMID:28400100; PMID:28757460; PMID:28757460; PMID:30316844; PMID:36880193; PMID:28849685; PMID:29031535; PMID:29061316; PMID:29486183; PMID:30104959; PMID:30265530; PMID:30316844; PMID:30935903; PMID:31173752; PMID:31194955; PMID:31313457; PMID:31332898; PMID:31638783; PMID:32043704; PMID:32954801; PMID:32980322; PMID:33094643; PMID:33212048; PMID:33491125; PMID:33522089; PMID:34047419; PMID:34121490; PMID:34228970; PMID:34826546; PMID:34971761; PMID:35202708; PMID:35901927; PMID:36058301; PMID:36567042; PMID:36880193; PMID:37121742; PMID:37648050; PMID:8558170; PMID:8679218; PMID:8853906; PMID:9184692
GO:0006919 Activation of cysteine-type endopeptidase activity involved in apoptotic process Increases phenotype PMID:26702581
GO:0006949 Syncytium formation Increases phenotype PMID:36336211
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:10986477; PMID:17045724; PMID:19153980; PMID:27402529; PMID:20820627; PMID:20820627; PMID:28343997; PMID:33645215; PMID:23225440; PMID:23325794; PMID:23325794; PMID:32107588; PMID:23352507; PMID:23940045; PMID:23954263; PMID:23994116; PMID:24371453; PMID:24371453; PMID:32220605; PMID:25127756; PMID:26856715; PMID:27402529; PMID:28286206; PMID:28343997; PMID:28400100; PMID:28400100; PMID:32679257; PMID:29218508; PMID:29262311; PMID:30935903; PMID:29277637; PMID:29992723; PMID:31306736; PMID:31313457; PMID:31715134; PMID:32107588; PMID:32585298; PMID:33645215; PMID:33709623
GO:0006979 Response to oxidative stress Increases phenotype PMID:10419516; PMID:10419516; PMID:19780897; PMID:11114198; PMID:12623783; PMID:12646174; PMID:12684028; PMID:15212121; PMID:15670758; PMID:16678324; PMID:17620961; PMID:19029647; PMID:19852698; PMID:20335659; PMID:20574816; PMID:20665104; PMID:21511693; PMID:22495766; PMID:22606287; PMID:23578882; PMID:23691207; PMID:33063357; PMID:7851416; PMID:8499460; PMID:8558170; PMID:9626573
GO:0007005 Mitochondrion organization Affects phenotype PMID:35202708
GO:0007006 Mitochondrial membrane organization Decreases phenotype PMID:34655286
GO:0007015 Actin filament organization Affects phenotype PMID:7851416
GO:0007049 Cell cycle Decreases phenotype PMID:10897038; PMID:15550384; PMID:24489904
GO:0007155 Cell adhesion Decreases phenotype PMID:28849685
GO:0007204 Positive regulation of cytosolic calcium ion concentration Increases phenotype PMID:15686499; PMID:26600069; PMID:27957685; PMID:28213291; PMID:28322340
GO:0008137 Nadh dehydrogenase (ubiquinone) activity Decreases phenotype PMID:30104959; PMID:31306736
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:29463041
GO:0008219 Cell death Increases phenotype PMID:10419516; PMID:10419516; PMID:20561156; PMID:10419516; PMID:9551854; PMID:10986477; PMID:11815240; PMID:14649725; PMID:14649725; PMID:15075382; PMID:31708532; PMID:15075382; PMID:16014620; PMID:16647178; PMID:17184924; PMID:17184924; PMID:18082333; PMID:17720870; PMID:18082333; PMID:18346863; PMID:18835041; PMID:20041988; PMID:20554019; PMID:20561156; PMID:20713718; PMID:20810208; PMID:21051700; PMID:21063783; PMID:21138464; PMID:21138464; PMID:27133439; PMID:21159781; PMID:21159781; PMID:22246807; PMID:21219333; PMID:21269327; PMID:22246807; PMID:22319455; PMID:22633977; PMID:22906069; PMID:22906069; PMID:30625984; PMID:23352507; PMID:23352507; PMID:27046792; PMID:23578882; PMID:24361291; PMID:24646700; PMID:24750999; PMID:25108166; PMID:25203460; PMID:25336634; PMID:26059411; PMID:26218895; PMID:26482937; PMID:26519223; PMID:26766292; PMID:26847702; PMID:26887594; PMID:27046792; PMID:27154496; PMID:27494022; PMID:27590588; PMID:28077425; PMID:28214884; PMID:28257953; PMID:28465020; PMID:28975372; PMID:29141199; PMID:29274434; PMID:29687528; PMID:30391638; PMID:30625984; PMID:30779908; PMID:31708532; PMID:31715134; PMID:33248029; PMID:39389441; PMID:9433676; PMID:9551854
GO:0008283 Cell population proliferation Increases phenotype PMID:14505808; PMID:17045724; PMID:15212121; PMID:17045724; PMID:18204935; PMID:1846307; PMID:19885844; PMID:22138401; PMID:22308036; PMID:23033007; PMID:23033007; PMID:25005833; PMID:25108166; PMID:23293585; PMID:23298159; PMID:23298159; PMID:25065601; PMID:23329528; PMID:23329528; PMID:27451028; PMID:23352507; PMID:24211421; PMID:24337227; PMID:24489904; PMID:24700636; PMID:24717318; PMID:24763052; PMID:24866057; PMID:24892553; PMID:25005833; PMID:25065601; PMID:25108166; PMID:25130202; PMID:25203460; PMID:25972194; PMID:26340163; PMID:26519223; PMID:26766292; PMID:27049278; PMID:27057282; PMID:27451028; PMID:27494022; PMID:27525270; PMID:34826546; PMID:37072838; PMID:9433676
GO:0008284 Positive regulation of cell population proliferation Affects phenotype PMID:24107596; PMID:24489904; PMID:27694308; PMID:30502458; PMID:31966594; PMID:36162953
GO:0008285 Negative regulation of cell population proliferation Increases phenotype PMID:15228596; PMID:18239155; PMID:18239155; PMID:36162953; PMID:20981859; PMID:24960579; PMID:27624276; PMID:27957685; PMID:27957685; PMID:28131760; PMID:28544404; PMID:28544404; PMID:29241734; PMID:29581108; PMID:30019796; PMID:30139380; PMID:30404999; PMID:30502458; PMID:30660577; PMID:30660577; PMID:32275923; PMID:31294882; PMID:31326407; PMID:31494107; PMID:32275923; PMID:34196753; PMID:34499403; PMID:34740634; PMID:36162953; PMID:36305173; PMID:37126988; PMID:37940031
GO:0008361 Regulation of cell size Affects phenotype PMID:15683462; PMID:7928003
GO:0008610 Lipid biosynthetic process Increases phenotype PMID:25130202; PMID:29499335; PMID:8404595
GO:0008631 Intrinsic apoptotic signaling pathway in response to oxidative stress Increases phenotype PMID:35196519
GO:0008652 Amino acid biosynthetic process Affects phenotype PMID:35227738
GO:0009008 Dna-methyltransferase activity Decreases phenotype PMID:37940031
GO:0009435 Nad biosynthetic process Decreases phenotype PMID:26218895
GO:0010508 Positive regulation of autophagy Increases phenotype PMID:26354380
GO:0010666 Positive regulation of cardiac muscle cell apoptotic process Increases phenotype PMID:34740634
GO:0010693 Negative regulation of alkaline phosphatase activity Increases phenotype PMID:20981859
GO:0010718 Positive regulation of epithelial to mesenchymal transition Increases phenotype PMID:32659284
GO:0010729 Positive regulation of hydrogen peroxide biosynthetic process Increases phenotype PMID:18357586; PMID:23000519; PMID:27255112; PMID:31885778; PMID:32525552
GO:0010823 Negative regulation of mitochondrion organization Increases phenotype PMID:30229906
GO:0010833 Telomere maintenance via telomere lengthening Decreases phenotype PMID:29309803
GO:0010917 Negative regulation of mitochondrial membrane potential Increases phenotype PMID:21138464; PMID:23691207; PMID:35112789; PMID:38166464
GO:0010918 Positive regulation of mitochondrial membrane potential Decreases phenotype PMID:24276018; PMID:24437944; PMID:24437944; PMID:25451577; PMID:25242411; PMID:25371773; PMID:25446858; PMID:25451577; PMID:25693864; PMID:28213291; PMID:28754375; PMID:30404999
GO:0010940 Positive regulation of necrotic cell death Increases phenotype PMID:15686499; PMID:22934841; PMID:24130165; PMID:26124276; PMID:26383629; PMID:26702581; PMID:30502458; PMID:32229109
GO:0010942 Positive regulation of cell death Increases phenotype PMID:16362428; PMID:16362428; PMID:19038359; PMID:19038359; PMID:19038359; PMID:19222219; PMID:19038359; PMID:21215799; PMID:19222219; PMID:21215799; PMID:23042718; PMID:24276018; PMID:24376630; PMID:24437944; PMID:24967384; PMID:25030372; PMID:25305479; PMID:25371773; PMID:25426952; PMID:25446858; PMID:25693864; PMID:26102013; PMID:26879219; PMID:27558805; PMID:27655674; PMID:27773815; PMID:28213291; PMID:28322340; PMID:28754375; PMID:30019796; PMID:30229906; PMID:30684454; PMID:31545955; PMID:31935365; PMID:38848825; PMID:9582369
GO:0010948 Negative regulation of cell cycle process Increases phenotype PMID:37940031
GO:0010972 Negative regulation of g2/m transition of mitotic cell cycle Increases phenotype PMID:31494107; PMID:38202631
GO:0014049 Positive regulation of glutamate secretion Increases phenotype PMID:34958835
GO:0014911 Positive regulation of smooth muscle cell migration Increases phenotype PMID:16632126
GO:0016042 Lipid catabolic process Increases phenotype PMID:21601209; PMID:23873220; PMID:25005833; PMID:25005833; PMID:25108166; PMID:25065601; PMID:25108166; PMID:26766292; PMID:27923645; PMID:28285367; PMID:28975372; PMID:29274434; PMID:29687528; PMID:29992723; PMID:30104959; PMID:31112013; PMID:31157476; PMID:31173752; PMID:31173752; PMID:31306736; PMID:31306736; PMID:32022557; PMID:32445656; PMID:33248029; PMID:33662508; PMID:33754447; PMID:8404595
GO:0016049 Cell growth Decreases phenotype PMID:23873220; PMID:29031535; PMID:29150332; PMID:29467594; PMID:29486183; PMID:29687528; PMID:30309986; PMID:30316844; PMID:30316844; PMID:30572915; PMID:30572915; PMID:30797899
GO:0016174 Nad(p)h oxidase h2o2-forming activity Increases phenotype PMID:28285367
GO:0016477 Cell migration Affects phenotype PMID:28214884; PMID:33412154; PMID:33491125
GO:0016505 Peptidase activator activity involved in apoptotic process Increases phenotype PMID:34499403
GO:0016567 Protein ubiquitination Increases phenotype PMID:21148404
GO:0016887 Atp hydrolysis activity Decreases phenotype PMID:31306736
GO:0018158 Protein oxidation Increases phenotype PMID:20981859; PMID:21658250; PMID:22495766; PMID:24437944; PMID:24437944; PMID:25065601; PMID:25451577; PMID:25005833; PMID:25065601; PMID:25451577; PMID:26102013; PMID:26766292; PMID:27923645; PMID:28285367; PMID:31306736; PMID:31969611; PMID:32679257; PMID:38574953
GO:0018212 Peptidyl-tyrosine modification Affects phenotype PMID:25211009
GO:0019530 Taurine metabolic process Affects phenotype PMID:35227738
GO:0019538 Protein metabolic process Affects phenotype PMID:35227738
GO:0019627 Urea metabolic process Affects phenotype PMID:29463041
GO:0019674 Nad metabolic process Affects phenotype PMID:30104959; PMID:35227738
GO:0019722 Calcium-mediated signaling Increases phenotype PMID:20574816
GO:0019752 Carboxylic acid metabolic process Affects phenotype PMID:35227738
GO:0019852 L-ascorbic acid metabolic process Affects phenotype PMID:28285367
GO:0019985 Translesion synthesis Increases phenotype PMID:31294882
GO:0030163 Protein catabolic process Affects phenotype PMID:7836468
GO:0030261 Chromosome condensation Increases phenotype PMID:30502458
GO:0030262 Apoptotic nuclear changes Increases phenotype PMID:30404999; PMID:31369745
GO:0030263 Apoptotic chromosome condensation Increases phenotype PMID:15142122; PMID:15228596
GO:0030282 Bone mineralization Affects phenotype PMID:27028516; PMID:31194955
GO:0030308 Negative regulation of cell growth Increases phenotype PMID:37894611
GO:0030334 Regulation of cell migration Affects phenotype PMID:24211779
GO:0030336 Negative regulation of cell migration Increases phenotype PMID:30139380; PMID:37126988
GO:0031324 Negative regulation of cellular metabolic process Increases phenotype PMID:36063024
GO:0031589 Cell-substrate adhesion Decreases phenotype PMID:24717318
GO:0032125 Micronucleus organization Increases phenotype PMID:29110037
GO:0032148 Activation of protein kinase b activity Affects phenotype PMID:18239155; PMID:21454801; PMID:28213291; PMID:31586451; PMID:36114797
GO:0032515 Negative regulation of phosphoprotein phosphatase activity Increases phenotype PMID:19038359
GO:0032760 Positive regulation of tumor necrosis factor production Affects phenotype PMID:23691207
GO:0032776 Dna methylation on cytosine Decreases phenotype PMID:37121742; PMID:37940031
GO:0032865 Ermes complex Increases phenotype PMID:36639873
GO:0032956 Regulation of actin cytoskeleton organization Decreases phenotype PMID:37640247
GO:0032964 Collagen biosynthetic process Decreases phenotype PMID:18341430; PMID:26766292; PMID:27028516
GO:0032966 Negative regulation of collagen biosynthetic process Increases phenotype PMID:20981859
GO:0032967 Positive regulation of collagen biosynthetic process Affects phenotype PMID:23570914
GO:0033138 Positive regulation of peptidyl-serine phosphorylation Increases phenotype PMID:24942733
GO:0033344 Cholesterol efflux Decreases phenotype PMID:33861588
GO:0033554 Cellular response to stress Increases phenotype PMID:9559875
GO:0033864 Positive regulation of nad(p)h oxidase activity Increases phenotype PMID:30710622
GO:0034113 Heterotypic cell-cell adhesion Increases phenotype PMID:37648050
GO:0034197 Triglyceride transport Affects phenotype PMID:32220030
GO:0034440 Lipid oxidation Increases phenotype PMID:20981859; PMID:21751221; PMID:24437944; PMID:24437944; PMID:25451577; PMID:36305173; PMID:24437944; PMID:36305173; PMID:25111876; PMID:25111876; PMID:34655286; PMID:25305479; PMID:25305479; PMID:37648050; PMID:25371773; PMID:25451577; PMID:28163957; PMID:28544404; PMID:29077241; PMID:29854080; PMID:31326407; PMID:32294493; PMID:32312157; PMID:34431445; PMID:36114797; PMID:37648050; PMID:38053484; PMID:38555047; PMID:38574953
GO:0034504 Protein localization to nucleus Affects phenotype PMID:36058301
GO:0034599 Cellular response to oxidative stress Affects phenotype PMID:30316844; PMID:35759867
GO:0034614 Cellular response to reactive oxygen species Increases phenotype PMID:23041154
GO:0035825 Homologous recombination Decreases phenotype PMID:33847444
GO:0036091 Positive regulation of transcription from rna polymerase ii promoter in response to oxidative stress Increases phenotype PMID:24437944
GO:0036164 Cell-abiotic substrate adhesion Affects phenotype PMID:33412154
GO:0036211 Protein modification process Increases phenotype PMID:23041154; PMID:25108166; PMID:25280774
GO:0036474 Cell death in response to hydrogen peroxide Increases phenotype PMID:23526725; PMID:28098360
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis Increases phenotype PMID:3049672
GO:0042060 Wound healing Affects phenotype PMID:26846883
GO:0042307 Positive regulation of protein import into nucleus Increases phenotype PMID:23041154; PMID:29667773; PMID:30660577
GO:0042310 Vasoconstriction Increases phenotype PMID:3518246; PMID:9465795
GO:0042360 Vitamin e metabolic process Affects phenotype PMID:28285367
GO:0042554 Superoxide anion generation Increases phenotype PMID:20433247; PMID:23293585; PMID:23873220; PMID:28285367; PMID:30104959; PMID:31162603; PMID:31306736; PMID:33662508; PMID:34896196
GO:0042743 Hydrogen peroxide metabolic process Increases phenotype PMID:20453712; PMID:22486562; PMID:23488790; PMID:24876631; PMID:25694362; PMID:26089033; PMID:27268782; PMID:27568464; PMID:28067054; PMID:28067054; PMID:32632975; PMID:28421826; PMID:28876976; PMID:30207182; PMID:30360616; PMID:30596275; PMID:31258454; PMID:31873818; PMID:31876186; PMID:32493877; PMID:32565124; PMID:32632975; PMID:32679048; PMID:32738378; PMID:32931794; PMID:32980475; PMID:33314588; PMID:33380422; PMID:33412154; PMID:33516661; PMID:33571619; PMID:33880675; PMID:33930485; PMID:34029635; PMID:34039237; PMID:34047412; PMID:34252510; PMID:34391839; PMID:34560125; PMID:34911549; PMID:35066937; PMID:35126122; PMID:35202708; PMID:35598716; PMID:35714946; PMID:36216167; PMID:36336211; PMID:36356655; PMID:36503300; PMID:36557995; PMID:36731763; PMID:36850985; PMID:37336463; PMID:38342389; PMID:39400474; PMID:39733793
GO:0042744 Hydrogen peroxide catabolic process Increases phenotype PMID:31162603; PMID:34958835
GO:0043065 Positive regulation of apoptotic process Increases phenotype PMID:11916964; PMID:15703382; PMID:16362428; PMID:16362428; PMID:24437944; PMID:25247703; PMID:25451577; PMID:36305173; PMID:20133810; PMID:20477944; PMID:22934841; PMID:23041154; PMID:23867156; PMID:24107596; PMID:24130165; PMID:24349266; PMID:24437944; PMID:24486147; PMID:25451577; PMID:26102013; PMID:26354380; PMID:26354380; PMID:36518482; PMID:26383629; PMID:28213291; PMID:28544404; PMID:29749404; PMID:30502331; PMID:30660577; PMID:30660577; PMID:32275923; PMID:31326407; PMID:31351048; PMID:31494107; PMID:32229109; PMID:32275923; PMID:34499403; PMID:36114797; PMID:36518482; PMID:37314160; PMID:37940031; PMID:38166464; PMID:38202631; PMID:39667565; PMID:9535218
GO:0043276 Anoikis Decreases phenotype PMID:21148404
GO:0043280 Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Increases phenotype PMID:26164594; PMID:33955754
GO:0043392 Negative regulation of dna binding Increases phenotype PMID:31162603
GO:0043970 Histone h3-k9 acetylation Increases phenotype PMID:26519223
GO:0043971 Histone h3-k18 acetylation Decreases phenotype PMID:27655674
GO:0044028 Dna hypomethylation Increases phenotype PMID:27624276
GO:0044154 Histone h3-k14 acetylation Increases phenotype PMID:26519223
GO:0044233 Mitochondria-associated endoplasmic reticulum membrane Increases phenotype PMID:36639873
GO:0044237 Cellular metabolic process Affects phenotype PMID:14696671; PMID:15878276; PMID:20433247; PMID:33847444; PMID:36880193; PMID:22108603; PMID:24717318; PMID:24925361; PMID:26218895; PMID:26286524; PMID:26286524; PMID:30104959; PMID:34121490; PMID:34971761; PMID:38942164; PMID:26422756; PMID:26447207; PMID:27267904; PMID:27430346; PMID:28214884; PMID:28214884; PMID:31054354; PMID:37648050; PMID:28285367; PMID:29658312; PMID:30104959; PMID:30296409; PMID:30296409; PMID:31066958; PMID:30625984; PMID:30625984; PMID:31173752; PMID:31306736; PMID:31521693; PMID:31638783; PMID:34077701; PMID:31157476; PMID:31173752; PMID:31194955; PMID:31306736; PMID:31313457; PMID:31332898; PMID:31638783; PMID:31941059; PMID:32043704; PMID:32334435; PMID:32954801; PMID:32980322; PMID:33094643; PMID:33212048; PMID:33248029; PMID:33522089; PMID:33631299; PMID:33847444; PMID:34047419; PMID:34077701; PMID:34121490; PMID:34228970; PMID:34302491; PMID:34971761; PMID:35202708; PMID:35478211; PMID:36058301; PMID:36093949; PMID:36639873; PMID:36880193; PMID:37121742; PMID:37648050; PMID:38942164; PMID:39109685
GO:0044242 Cellular lipid catabolic process Increases phenotype PMID:23041154
GO:0044319 Wound healing, spreading of cells Increases phenotype PMID:24152438; PMID:26519223; PMID:32980322
GO:0045023 G0 to g1 transition Affects phenotype PMID:14696671; PMID:34228970
GO:0045298 Tubulin complex Affects phenotype PMID:21658250
GO:0045333 Cellular respiration Decreases phenotype PMID:14760497; PMID:26422756
GO:0045444 Fat cell differentiation Decreases phenotype PMID:24740755
GO:0045454 Cell redox homeostasis Decreases phenotype PMID:27624276; PMID:27842206; PMID:28849685; PMID:29803841; PMID:31445075; PMID:37640247
GO:0045647 Negative regulation of erythrocyte differentiation Increases phenotype PMID:34581912
GO:0045668 Negative regulation of osteoblast differentiation Increases phenotype PMID:20981859
GO:0045860 Positive regulation of protein kinase activity Affects phenotype PMID:7851416
GO:0045919 Positive regulation of cytolysis Increases phenotype PMID:15228596; PMID:18239155; PMID:34499403; PMID:34740634; PMID:36114797
GO:0045930 Negative regulation of mitotic cell cycle Increases phenotype PMID:23873220; PMID:28343997; PMID:29110037
GO:0046034 Atp metabolic process Affects phenotype PMID:35202708; PMID:36639873
GO:0046134 Pyrimidine nucleoside biosynthetic process Increases phenotype PMID:27119504
GO:0046209 Nitric oxide metabolic process Affects phenotype PMID:26422756; PMID:37648050; PMID:39425453
GO:0046325 Negative regulation of glucose import Affects phenotype PMID:24221993
GO:0046326 Positive regulation of glucose import Affects phenotype PMID:24221993
GO:0046330 Positive regulation of jnk cascade Increases phenotype PMID:34741589
GO:0046466 Membrane lipid catabolic process Increases phenotype PMID:10580364; PMID:12093485; PMID:12566129; PMID:15528046; PMID:17551831; PMID:19029647; PMID:1998525; PMID:1998525; PMID:8074069; PMID:20574816; PMID:2634830; PMID:3020934; PMID:3587766; PMID:7474556; PMID:8074069; PMID:8609595; PMID:8891671; PMID:9139234
GO:0046500 S-adenosylmethionine metabolic process Increases phenotype PMID:27624276
GO:0046710 Gdp metabolic process Affects phenotype PMID:35227738
GO:0046911 Metal chelating activity Increases phenotype PMID:27046792
GO:0047823 D-glutamyltransferase activity Increases phenotype PMID:30461186
GO:0048308 Organelle inheritance Affects phenotype PMID:28343997
GO:0050665 Hydrogen peroxide biosynthetic process Increases phenotype PMID:23374533; PMID:27323401; PMID:30195209; PMID:31710167; PMID:31715309; PMID:32061760; PMID:32097678; PMID:34635930
GO:0051092 Positive regulation of nf-kappab transcription factor activity Increases phenotype PMID:12076508; PMID:22387535; PMID:24558376; PMID:31306736; PMID:9582369
GO:0051259 Protein complex oligomerization Increases phenotype PMID:29229420
GO:0051260 Protein homooligomerization Affects phenotype PMID:25211009; PMID:28343033
GO:0051281 Positive regulation of release of sequestered calcium ion into cytosol Increases phenotype PMID:23885834
GO:0051354 Negative regulation of oxidoreductase activity Increases phenotype PMID:31162603
GO:0051409 Response to nitrosative stress Affects phenotype PMID:23691207
GO:0051560 Mitochondrial calcium ion homeostasis Affects phenotype PMID:34971761
GO:0051654 Establishment of mitochondrion localization Affects phenotype PMID:25693864
GO:0051881 Regulation of mitochondrial membrane potential Increases phenotype PMID:12623783; PMID:14505808; PMID:16259763; PMID:20674559; PMID:21431366; PMID:23293585; PMID:23329528; PMID:23329528; PMID:27451028; PMID:26218895; PMID:26422756; PMID:27046792; PMID:27451028; PMID:28400100; PMID:29061316; PMID:29902531; PMID:30104959; PMID:30104959; PMID:34971761; PMID:30316844; PMID:31306736; PMID:34971761; PMID:36639873; PMID:38555047
GO:0051882 Mitochondrial depolarization Increases phenotype PMID:33212048; PMID:33248029; PMID:34971761; PMID:35202708
GO:0051899 Membrane depolarization Increases phenotype PMID:36639873
GO:0055069 Zinc ion homeostasis Decreases phenotype PMID:30779908; PMID:34958835
GO:0055074 Calcium ion homeostasis Affects phenotype PMID:29061316; PMID:30779908
GO:0055089 Fatty acid homeostasis Decreases phenotype PMID:28163957
GO:0060271 Cilium assembly Increases phenotype PMID:33526986
GO:0060326 Cell chemotaxis Affects phenotype PMID:32043704; PMID:33094643; PMID:33412154
GO:0061045 Negative regulation of wound healing Increases phenotype PMID:38202631
GO:0061089 Negative regulation of sequestering of zinc ion Increases phenotype PMID:30229906
GO:0061090 Positive regulation of sequestering of zinc ion Increases phenotype PMID:30229906
GO:0061092 Positive regulation of phospholipid translocation Decreases phenotype PMID:20946910
GO:0061691 Detoxification of hydrogen peroxide Increases phenotype PMID:23452429
GO:0061692 Cellular detoxification of hydrogen peroxide Increases phenotype PMID:22308036
GO:0061739 Protein lipidation involved in autophagosome assembly Increases phenotype PMID:31563593; PMID:34740634
GO:0062100 Positive regulation of programmed necrotic cell death Increases phenotype PMID:35112789
GO:0070168 Negative regulation of biomineral tissue development Increases phenotype PMID:20981859
GO:0070212 Protein poly-adp-ribosylation Increases phenotype PMID:15976037; PMID:29970481; PMID:22940495; PMID:22940495; PMID:29970481; PMID:23994116; PMID:26218895; PMID:26383629; PMID:26383632; PMID:26383632; PMID:26492236; PMID:28001384; PMID:29317476; PMID:29970481; PMID:30139380; PMID:30502458; PMID:31494107; PMID:34519134; PMID:35778544
GO:0070265 Necrotic cell death Increases phenotype PMID:15878276; PMID:23165319; PMID:25673179; PMID:28849685; PMID:34228970; PMID:34979142; PMID:36807289
GO:0070267 Oncosis Increases phenotype PMID:26124276; PMID:26766292
GO:0070269 Pyroptosis Increases phenotype PMID:33955754
GO:0070301 Cellular response to hydrogen peroxide Increases phenotype PMID:23891692; PMID:26519223; PMID:27655674
GO:0070328 Triglyceride homeostasis Decreases phenotype PMID:29317476
GO:0070374 Positive regulation of erk1 and erk2 cascade Increases phenotype PMID:16386719; PMID:25451577
GO:0070509 Calcium ion import Increases phenotype PMID:24646700
GO:0070994 Detection of oxidative stress Increases phenotype PMID:24876631; PMID:24925361; PMID:26163455; PMID:26482937; PMID:29185360; PMID:29185360; PMID:36880193; PMID:32031418; PMID:32954801; PMID:32976959; PMID:33094643; PMID:34121490; PMID:34427160; PMID:34651546; PMID:34906654; PMID:36028061; PMID:36567042; PMID:36608876; PMID:36639873; PMID:36907384; PMID:37121742; PMID:37286014; PMID:37659625; PMID:38574953; PMID:38799687; PMID:39089415; PMID:39299373; PMID:39843243
GO:0070997 Neuron death Increases phenotype PMID:25461191
GO:0071103 Dna conformation change Increases phenotype PMID:28286206
GO:0071442 Positive regulation of histone h3-k14 acetylation Decreases phenotype PMID:27655674
GO:0071493 Cellular response to uv-b Increases phenotype PMID:30456849
GO:0071722 Detoxification of arsenic-containing substance Decreases phenotype PMID:27721063
GO:0071763 Nuclear membrane organization Decreases phenotype PMID:25280774
GO:0071902 Positive regulation of protein serine/threonine kinase activity Increases phenotype PMID:20224005
GO:0071926 Endocannabinoid signaling pathway Affects phenotype PMID:28285367
GO:0072593 Reactive oxygen species metabolic process Increases phenotype PMID:18164200; PMID:20433247; PMID:33847444; PMID:36336871; PMID:21376117; PMID:23293585; PMID:23298159; PMID:23298159; PMID:23833438; PMID:38942164; PMID:23535287; PMID:23535287; PMID:25111660; PMID:23619996; PMID:24040102; PMID:24075811; PMID:24590062; PMID:24700636; PMID:24733848; PMID:24759736; PMID:24844443; PMID:25005833; PMID:25111660; PMID:25130202; PMID:25855085; PMID:36058301; PMID:26006730; PMID:26409248; PMID:26422756; PMID:26447207; PMID:26513129; PMID:28214884; PMID:28214884; PMID:37648050; PMID:28285367; PMID:30104959; PMID:31953210; PMID:32061760; PMID:34077701; PMID:32167238; PMID:32312157; PMID:32525701; PMID:32917723; PMID:32980322; PMID:33130239; PMID:33131013; PMID:33212048; PMID:33248029; PMID:33360347; PMID:33422634; PMID:33662508; PMID:33847444; PMID:34047419; PMID:34077701; PMID:34369038; PMID:34774662; PMID:34826546; PMID:34896196; PMID:34953976; PMID:35123994; PMID:35279910; PMID:35457321; PMID:35478211; PMID:35478211; PMID:37031912; PMID:35714946; PMID:35901927; PMID:36058301; PMID:36070022; PMID:36336871; PMID:36503300; PMID:36868496; PMID:37031912; PMID:37648050; PMID:37659621; PMID:37850667; PMID:37981056; PMID:38040126; PMID:38042493; PMID:38053484; PMID:38325586; PMID:38555047; PMID:38574953; PMID:38942164; PMID:39299373; PMID:39431643; PMID:39743035
GO:0072655 Establishment of protein localization to mitochondrion Increases phenotype PMID:29229420
GO:0080111 Dna demethylation Increases phenotype PMID:37121742
GO:0080129 Proteasome core complex assembly Increases phenotype PMID:31969611
GO:0090116 C-5 methylation of cytosine Decreases phenotype PMID:27624276
GO:0090141 Positive regulation of mitochondrial fission Increases phenotype PMID:23867156
GO:0090200 Positive regulation of release of cytochrome c from mitochondria Increases phenotype PMID:15703382; PMID:25242411; PMID:26164594; PMID:30404999
GO:0090398 Cellular senescence Increases phenotype PMID:19471118; PMID:19471118; PMID:25512378; PMID:8824885; PMID:23859249; PMID:26443543; PMID:25512378; PMID:26443543; PMID:27049278; PMID:27049278; PMID:33491125; PMID:28526263; PMID:28739487; PMID:33491125; PMID:36500241; PMID:36567042
GO:0090403 Oxidative stress-induced premature senescence Increases phenotype PMID:16259763; PMID:18957176; PMID:35759867
GO:0097352 Autophagosome maturation Increases phenotype PMID:24912985
GO:0097692 Histone h3-k4 monomethylation Increases phenotype PMID:27655674
GO:0097707 Ferroptosis Increases phenotype PMID:30797899
GO:0098659 Inorganic cation import across plasma membrane Increases phenotype PMID:27957685
GO:0098869 Cellular oxidant detoxification Increases phenotype PMID:28986287
GO:0098990 Ampa selective glutamate receptor signaling pathway Increases phenotype PMID:34958835
GO:0140042 Lipid droplet formation Increases phenotype PMID:31705858
GO:0150033 Negative regulation of protein localization to lysosome Increases phenotype PMID:30229906
GO:1900163 Positive regulation of phospholipid scramblase activity Decreases phenotype PMID:20946910
GO:1900181 Negative regulation of protein localization to nucleus Increases phenotype PMID:31162603
GO:1900182 Positive regulation of protein localization to nucleus Increases phenotype PMID:31162603; PMID:32275923; PMID:34655286
GO:1900409 Positive regulation of cellular response to oxidative stress Increases phenotype PMID:36162953
GO:1900745 Positive regulation of p38mapk cascade Increases phenotype PMID:15228596; PMID:16362428; PMID:16362428; PMID:19038359; PMID:25451577; PMID:16386719; PMID:19038359; PMID:25451577; PMID:28213291; PMID:34741589
GO:1901098 Positive regulation of autophagosome maturation Decreases phenotype PMID:24889822
GO:1901216 Positive regulation of neuron death Increases phenotype PMID:34958835
GO:1901224 Positive regulation of nik/nf-kappab signaling Increases phenotype PMID:16259763; PMID:18957176; PMID:19509257; PMID:25451577
GO:1901300 Positive regulation of hydrogen peroxide-mediated programmed cell death Increases phenotype PMID:23829535; PMID:35196519
GO:1901666 Positive regulation of nad+ adp-ribosyltransferase activity Increases phenotype PMID:15976037; PMID:22940495; PMID:26383632; PMID:26600069; PMID:27515310; PMID:27694308; PMID:28322340; PMID:31494107
GO:1901668 Regulation of superoxide dismutase activity Increases phenotype PMID:35196519; PMID:36518482
GO:1901670 Negative regulation of superoxide dismutase activity Increases phenotype PMID:22867017; PMID:23691207; PMID:26164594; PMID:28544404; PMID:30911355; PMID:31326407; PMID:34499403; PMID:34655286; PMID:36114797; PMID:36305173
GO:1901671 Positive regulation of superoxide dismutase activity Decreases phenotype PMID:25305479; PMID:25451577
GO:1901676 Positive regulation of histone h3-k27 acetylation Decreases phenotype PMID:27655674
GO:1901687 Glutathione derivative biosynthetic process Increases phenotype PMID:28754375
GO:1901856 Negative regulation of cellular respiration Increases phenotype PMID:30502458
GO:1902046 Positive regulation of fas signaling pathway Increases phenotype PMID:20946910
GO:1902108 Regulation of mitochondrial membrane permeability involved in apoptotic process Affects phenotype PMID:26164594
GO:1902310 Positive regulation of peptidyl-serine dephosphorylation Increases phenotype PMID:24942733
GO:1902466 Positive regulation of histone h3-k27 trimethylation Increases phenotype PMID:27655674
GO:1902512 Positive regulation of apoptotic dna fragmentation Increases phenotype PMID:11597122; PMID:15228596; PMID:18850225; PMID:23542513; PMID:23885834; PMID:25726415; PMID:27773815; PMID:34740634
GO:1902552 Negative regulation of catalase activity Increases phenotype PMID:23691207; PMID:26164594
GO:1902690 Positive regulation of nad metabolic process Increases phenotype PMID:15075382; PMID:18239155; PMID:26383629; PMID:29317476; PMID:30139380; PMID:30502458
GO:1903047 Mitotic cell cycle process Affects phenotype PMID:14696671; PMID:34228970
GO:1903283 Negative regulation of glutathione peroxidase activity Increases phenotype PMID:23691207; PMID:26164594; PMID:28163957; PMID:31326407; PMID:36518482
GO:1903284 Positive regulation of glutathione peroxidase activity Decreases phenotype PMID:25305479; PMID:25451577
GO:1903378 Positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway Increases phenotype PMID:25304210; PMID:25975093
GO:1903409 Reactive oxygen species biosynthetic process Increases phenotype PMID:14505808; PMID:17045724; PMID:15686499; PMID:16647178; PMID:17045724; PMID:19194971; PMID:19194971; PMID:28343997; PMID:19222219; PMID:19723100; PMID:19723100; PMID:30316844; PMID:30572915; PMID:21159781; PMID:22289031; PMID:23033007; PMID:23033007; PMID:25108166; PMID:23352507; PMID:23546295; PMID:29486183; PMID:24173369; PMID:24173369; PMID:26519223; PMID:25108166; PMID:25655391; PMID:25655391; PMID:27451028; PMID:27057282; PMID:27133439; PMID:27154496; PMID:27178040; PMID:27180073; PMID:27451028; PMID:27494022; PMID:27525270; PMID:27590588; PMID:27939242; PMID:28300663; PMID:28533128; PMID:28739487; PMID:28960787; PMID:29061316; PMID:29061316; PMID:31306736; PMID:31638783; PMID:29274434; PMID:29274434; PMID:31157476; PMID:29362861; PMID:29486183; PMID:29687528; PMID:29992683; PMID:30243730; PMID:30316844; PMID:30461186; PMID:30572915; PMID:30842373; PMID:31112013; PMID:31157476; PMID:31194955; PMID:31306686; PMID:31306736; PMID:31313457; PMID:31332898; PMID:31638783; PMID:31696622; PMID:31705858; PMID:31715134; PMID:33955754
GO:1903427 Negative regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:37918281
GO:1903428 Positive regulation of reactive oxygen species biosynthetic process Increases phenotype PMID:12874837; PMID:16151469; PMID:16362428; PMID:16362428; PMID:19038359; PMID:24437944; PMID:25247703; PMID:27484784; PMID:19038359; PMID:22659117; PMID:22902249; PMID:23325087; PMID:23691207; PMID:23891692; PMID:24142884; PMID:24157872; PMID:24157872; PMID:25320179; PMID:25354548; PMID:24437944; PMID:24889822; PMID:24929095; PMID:25242411; PMID:25305479; PMID:25305479; PMID:36162953; PMID:37640247; PMID:25321315; PMID:25354548; PMID:25446499; PMID:25446858; PMID:25496033; PMID:25496033; PMID:25686467; PMID:25950987; PMID:28213291; PMID:28302478; PMID:30244016; PMID:32119866; PMID:25693864; PMID:25716161; PMID:25726415; PMID:26141520; PMID:26164594; PMID:26187750; PMID:26231820; PMID:26341179; PMID:26686574; PMID:26702581; PMID:26867644; PMID:26938529; PMID:26975474; PMID:27478981; PMID:27624276; PMID:27693598; PMID:31966594; PMID:28112004; PMID:28131760; PMID:28192182; PMID:28213291; PMID:28321046; PMID:28321046; PMID:29893964; PMID:28450277; PMID:28703385; PMID:28986287; PMID:29058724; PMID:29289706; PMID:29665407; PMID:29893964; PMID:29964313; PMID:30036487; PMID:30103639; PMID:30139380; PMID:30229906; PMID:30404999; PMID:30502353; PMID:30660577; PMID:30660577; PMID:32275923; PMID:30709899; PMID:30710622; PMID:31401084; PMID:31966594; PMID:32004531; PMID:32275923; PMID:32672941; PMID:32714076; PMID:32745495; PMID:32956829; PMID:34302933; PMID:34499403; PMID:34741589; PMID:35112789; PMID:35122928; PMID:35710092; PMID:36114797; PMID:36162953; PMID:36186093; PMID:37640247; PMID:38166464; PMID:38202631
GO:1903580 Positive regulation of atp metabolic process Increases phenotype PMID:18239155; PMID:30502458
GO:1903626 Positive regulation of dna catabolic process Increases phenotype PMID:21751221; PMID:32229109; PMID:35710092
GO:1903752 Positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Increases phenotype PMID:25975093; PMID:28112004; PMID:29902531; PMID:33955754; PMID:36186093
GO:1903945 Positive regulation of hepatocyte apoptotic process Increases phenotype PMID:32579217
GO:1904960 Positive regulation of cytochrome-c oxidase activity Increases phenotype PMID:19306371
GO:1905206 Positive regulation of hydrogen peroxide-induced cell death Increases phenotype PMID:31431007; PMID:32023790; PMID:35883890
GO:1905267 Endonucleolytic cleavage involved in trna processing Increases phenotype PMID:29431851
GO:1905665 Positive regulation of calcium ion import across plasma membrane Increases phenotype PMID:29658714
GO:1905672 Negative regulation of lysosome organization Increases phenotype PMID:30229906
GO:1905955 Negative regulation of endothelial tube morphogenesis Increases phenotype PMID:30139380
GO:1990404 Nad+-protein adp-ribosyltransferase activity Increases phenotype PMID:20820627
GO:2000379 Positive regulation of reactive oxygen species metabolic process Affects phenotype PMID:23570914
GO:2000470 Positive regulation of peroxidase activity Increases phenotype PMID:28754375
GO:2000617 Positive regulation of histone h3-k9 acetylation Affects phenotype PMID:20705415; PMID:27655674
GO:2000653 Regulation of genetic imprinting Decreases phenotype PMID:24558376
GO:2000679 Positive regulation of transcription regulatory region dna binding Increases phenotype PMID:31162603
GO:2000774 Positive regulation of cellular senescence Increases phenotype PMID:30139380; PMID:32949572
GO:2000786 Positive regulation of autophagosome assembly Increases phenotype PMID:34740634
GO:2001171 Positive regulation of atp biosynthetic process Decreases phenotype PMID:28754375
GO:2001244 Positive regulation of intrinsic apoptotic signaling pathway Increases phenotype PMID:28341137
GO:2001259 Positive regulation of cation channel activity Increases phenotype PMID:28603015
GO:2001290 Hydroperoxide metabolic process Affects phenotype PMID:33720505; PMID:33992719
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.