| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0001503 | Ossification | Decreases phenotype | PMID:30561715 |
| GO:0001958 | Endochondral ossification | Decreases phenotype | PMID:32976586 |
| GO:0005764 | Lysosome | Decreases phenotype | PMID:38603619 |
| GO:0007005 | Mitochondrion organization | Affects phenotype | PMID:35135005 |
| GO:0007040 | Lysosome organization | Decreases phenotype | PMID:35135005 |
| GO:0008219 | Cell death | Increases phenotype | PMID:31404653 |
| GO:0016477 | Cell migration | Decreases phenotype | PMID:33969458 |
| GO:0032930 | Positive regulation of superoxide anion generation | Increases phenotype | PMID:26794138 |
| GO:0048709 | Oligodendrocyte differentiation | Decreases phenotype | PMID:33969458 |
| GO:0051216 | Cartilage development | Decreases phenotype | PMID:30561715 |
| GO:0051882 | Mitochondrial depolarization | Increases phenotype | PMID:31404653 |
| GO:0060351 | Cartilage development involved in endochondral bone morphogenesis | Decreases phenotype | PMID:32976586 |
| GO:0060536 | Cartilage morphogenesis | Decreases phenotype | PMID:32976586 |
| GO:0072593 | Reactive oxygen species metabolic process | Affects phenotype | PMID:36813253 |
| GO:0098508 | Endothelial to hematopoietic transition | Increases phenotype | PMID:31404653 |
| GO:0140042 | Lipid droplet formation | Increases phenotype | PMID:35135005; PMID:38603619 |
| GO:1903428 | Positive regulation of reactive oxygen species biosynthetic process | Increases phenotype | PMID:35135005 |
| GO:2000866 | Positive regulation of estradiol secretion | Increases phenotype | PMID:38603619 |
| GO:2000872 | Positive regulation of progesterone secretion | Increases phenotype | PMID:26794138; PMID:38603619 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.