Difenoconazole


Curated chemical-phenotype interactions from CTD
GO IDGO nameInteraction typeReference
GO:0000737 Dna catabolic process, endonucleolytic Increases phenotype PMID:34519103
GO:0001843 Neural tube closure Decreases phenotype PMID:28263823
GO:0002072 Optic cup morphogenesis involved in camera-type eye development Decreases phenotype PMID:28263823
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity Increases phenotype PMID:34425431
GO:0004303 Estradiol 17-beta-dehydrogenase activity Decreases phenotype PMID:34519103
GO:0004602 Glutathione peroxidase activity Increases phenotype PMID:34519103
GO:0004784 Superoxide dismutase activity Increases phenotype PMID:34425431
GO:0006006 Glucose metabolic process Affects phenotype PMID:34425431
GO:0006090 Pyruvate metabolic process Affects phenotype PMID:34425431
GO:0006631 Fatty acid metabolic process Affects phenotype PMID:34425431
GO:0006641 Triglyceride metabolic process Affects phenotype PMID:32810590; PMID:33575850; PMID:34425431
GO:0006749 Glutathione metabolic process Affects phenotype PMID:34425431
GO:0006974 Cellular response to dna damage stimulus Increases phenotype PMID:19591892
GO:0007283 Spermatogenesis Decreases phenotype PMID:34519103
GO:0008203 Cholesterol metabolic process Affects phenotype PMID:34425431
GO:0010942 Positive regulation of cell death Increases phenotype PMID:40434365
GO:0016042 Lipid catabolic process Increases phenotype PMID:28679351
GO:0030520 Intracellular estrogen receptor signaling pathway Affects phenotype PMID:39365753
GO:0030521 Androgen receptor signaling pathway Affects phenotype PMID:39365753
GO:0034101 Erythrocyte homeostasis Decreases phenotype PMID:28679351
GO:0045540 Regulation of cholesterol biosynthetic process Decreases phenotype PMID:25419412
GO:0046449 Creatinine metabolic process Affects phenotype PMID:25419412
GO:0050810 Regulation of steroid biosynthetic process Affects phenotype PMID:26781511
GO:0055007 Cardiac muscle cell differentiation Decreases phenotype PMID:29337257
GO:0060037 Pharyngeal system development Decreases phenotype PMID:28263823
GO:0061370 Testosterone biosynthetic process Affects phenotype PMID:34519103
GO:0070265 Necrotic cell death Increases phenotype PMID:28679351
GO:0097722 Sperm motility Decreases phenotype PMID:34519103
GO:0140042 Lipid droplet formation Increases phenotype PMID:34425431
GO:2000609 Regulation of thyroid hormone generation Affects phenotype PMID:25419412
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.