| GO ID | GO name | Interaction type | Reference |
|---|---|---|---|
| GO:0002157 | Positive regulation of thyroid hormone mediated signaling pathway | Increases phenotype | PMID:30818834 |
| GO:0006096 | Glycolytic process | Increases phenotype | PMID:32607615 |
| GO:0006754 | Atp biosynthetic process | Decreases phenotype | PMID:29127035 |
| GO:0006974 | Cellular response to dna damage stimulus | Increases phenotype | PMID:19591892 |
| GO:0008219 | Cell death | Increases phenotype | PMID:32607615 |
| GO:0008283 | Cell population proliferation | Affects phenotype | PMID:29127035; PMID:34642769 |
| GO:0010917 | Negative regulation of mitochondrial membrane potential | Increases phenotype | PMID:30818834 |
| GO:0019432 | Triglyceride biosynthetic process | Increases phenotype | PMID:29127035 |
| GO:0031175 | Neuron projection development | Decreases phenotype | PMID:33512557 |
| GO:0044237 | Cellular metabolic process | Decreases phenotype | PMID:32607615; PMID:32607615; PMID:34642769 |
| GO:0045333 | Cellular respiration | Decreases phenotype | PMID:32607615; PMID:33512557 |
| GO:0046034 | Atp metabolic process | Affects phenotype | PMID:33512557; PMID:34642769 |
| GO:0048386 | Positive regulation of retinoic acid receptor signaling pathway | Increases phenotype | PMID:30818834 |
| GO:0051881 | Regulation of mitochondrial membrane potential | Affects phenotype | PMID:29127035; PMID:32607615; PMID:32607615; PMID:34642769; PMID:33512557 |
| GO:1990787 | Negative regulation of hh target transcription factor activity | Increases phenotype | PMID:30818834 |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.