4,4'-(Octahydro-4,7-methano-5H-inden-5-ylidene)bisphenol

• Identification
• Experimental evidence
• Physicochemical properties
• ADMET properties
• Chemical-gene interaction
• Descriptors
• Presence in chemical regulation or guideline
• Presence in human biospecimen

Literature identifier	Study type	Test dosage	Effective dosage	Endocrine-mediated endpoints	Systems-level perturbations
PMID:17904329	IVR	1000 mg/kg/day	1000 mg/kg/day	Uterotrophic effect	Reproductive endocrine-mediated perturbations
PMID:19882337	IVR	10 mg/kg/day	10 mg/kg/day	Abnormal estrous cycles	Reproductive endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Decreased liver weights	Hepatic endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Decreased prostate weights	Reproductive endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Decreased weights of pituitary gland	Neurological endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Decreased weights of seminal vesicles	Reproductive endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Affects uterine morphology	Reproductive endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Hyperplasia in thyroid gland	Metabolic endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Affects ovarian follicles population	Reproductive endocrine-mediated perturbations
	IVR	50 mg/kg/day	50 mg/kg/day	Hyperplasia in thyroid gland	Metabolic endocrine-mediated perturbations
	IVR	50 mg/kg/day	50 mg/kg/day	Decreased prostate weights	Reproductive endocrine-mediated perturbations
	IVR	50 mg/kg/day	50 mg/kg/day	Decreased liver weights	Hepatic endocrine-mediated perturbations
	IVR	50 mg/kg/day	50 mg/kg/day	Decreased weights of seminal vesicles	Reproductive endocrine-mediated perturbations
	IVR	50 mg/kg/day	50 mg/kg/day	Decreased weights of pituitary gland	Neurological endocrine-mediated perturbations
	IVR	250 mg/kg/day	250 mg/kg/day	Decreased prostate weights	Reproductive endocrine-mediated perturbations
	IVR	250 mg/kg/day	250 mg/kg/day	Decreased liver weights	Hepatic endocrine-mediated perturbations
	IVR	250 mg/kg/day	250 mg/kg/day	Changes in haemocrit values	Immunological endocrine-mediated perturbations
	IVR	250 mg/kg/day	250 mg/kg/day	Decreased weights of seminal vesicles	Reproductive endocrine-mediated perturbations
	IVR	250 mg/kg/day	250 mg/kg/day	Hyperplasia in thyroid gland	Metabolic endocrine-mediated perturbations
	IVR	250 mg/kg/day	250 mg/kg/day	Decreased weights of pituitary gland	Neurological endocrine-mediated perturbations

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