Diisononyl hexahydrophthalate

• Identification
• Experimental evidence
• Physicochemical properties
• ADMET properties
• Chemical-gene interaction
• Descriptors
• Presence in chemical regulation or guideline
• Presence in human biospecimen

Literature identifier	Study type	Test dosage	Effective dosage	Endocrine-mediated endpoints	Systems-level perturbations
PMID:29945229	IVR	30 mg/kg	30 mg/kg	Affects testicular function	Reproductive endocrine-mediated perturbations
	IVR	300 mg/kg	300 mg/kg	Affects testicular function	Reproductive endocrine-mediated perturbations
PMID:31605871	IVR	100 mg/kg/day	100 mg/kg/day	Affects superoxide dismutase (SOD) levels	Hepatic endocrine-mediated perturbations
	IVR	100 mg/kg/day	100 mg/kg/day	Affects liver function	Hepatic endocrine-mediated perturbations
	IVR	100 mg/kg/day	100 mg/kg/day	Affects bile acid pathway	Metabolic endocrine-mediated perturbations
	IVR	100 mg/kg/day	100 mg/kg/day	Affects lipid metabolism	Metabolic endocrine-mediated perturbations
	IVR	100 mg/kg/day	100 mg/kg/day	Affects steroid metabolism	Metabolic endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
	IVR	100 mg/kg/day	100 mg/kg/day	Alterations in immune responses	Immunological endocrine-mediated perturbations
	IVR	100 mg/kg/day	100 mg/kg/day	Affects lipid metabolism in offspring	Developmental endocrine-mediated perturbations;Metabolic endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Affects liver function	Hepatic endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Affects superoxide dismutase (SOD) levels	Hepatic endocrine-mediated perturbations
	IVR	10 mg/kg/day	10 mg/kg/day	Affects steroid metabolism	Metabolic endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
	IVR	1 mg/kg/day	1 mg/kg/day	Affects steroid metabolism	Metabolic endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
	IVR	1 mg/kg/day	1 mg/kg/day	Affects bile acid pathway	Metabolic endocrine-mediated perturbations
	IVR	1 mg/kg/day	1 mg/kg/day	Affects liver function	Hepatic endocrine-mediated perturbations
	IVR	1 mg/kg/day	1 mg/kg/day	Affects lipid metabolism in offspring	Developmental endocrine-mediated perturbations;Metabolic endocrine-mediated perturbations
	IVR	1 mg/kg/day	1 mg/kg/day	Alterations in immune responses	Immunological endocrine-mediated perturbations
	IVR	1 mg/kg/day	1 mg/kg/day	Affects lipid metabolism	Metabolic endocrine-mediated perturbations

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