2,4-Diethyl-9H-thioxanthen-9-one


Literature identifierStudy typeTest dosageEffective dosageEndocrine-mediated endpointsSystems-level perturbations
PMID:23208609IVTH0.0000001 - 0.00005 M 0.000001 - 0.00005 MAffects steroidogenesisReproductive endocrine-mediated perturbations
IVTH0.000001 M 0.000001 MDecreased estrone levelsReproductive endocrine-mediated perturbations
IVTH0.000001 M 0.000001 MDecreased estradiol levelsReproductive endocrine-mediated perturbations
IVTH0.00001 M 0.00001 MDecreased 17-OH-progesterone levelsReproductive endocrine-mediated perturbations
IVTH0.00001 M 0.00001 MDecreased progesterone levelsReproductive endocrine-mediated perturbations
IVTH0.00001 M 0.00001 MDecreased estrone levelsReproductive endocrine-mediated perturbations
IVTH0.00001 M 0.00001 MDecreased androstenedione levelsReproductive endocrine-mediated perturbations
IVTH0.00005 M 0.00005 MDecreased progesterone levelsReproductive endocrine-mediated perturbations
IVTH0.00001 M 0.00001 MDecreased estradiol levelsReproductive endocrine-mediated perturbations
IVTH0.00005 M 0.00005 MDecreased estradiol levelsReproductive endocrine-mediated perturbations
IVTH0.00001 M 0.00001 MDecreased 17-OH-pregnenolone levelsReproductive endocrine-mediated perturbations
IVTH0.00005 M 0.00005 MDecreased 17-OH-progesterone levelsReproductive endocrine-mediated perturbations
IVTH0.00001 M 0.00001 MDecreased Dehydroepiandrosterone (DHEA) levelsMetabolic endocrine-mediated perturbations
IVTH0.00005 M 0.00005 MDecreased pregnenolone levelsReproductive endocrine-mediated perturbations
IVTH0.000005 M 0.000005 MDecreased 17-OH-progesterone levelsReproductive endocrine-mediated perturbations
IVTH0.000005 M 0.000005 MDecreased Dehydroepiandrosterone (DHEA) levelsMetabolic endocrine-mediated perturbations
IVTH0.000005 M 0.000005 MDecreased 17-OH-pregnenolone levelsReproductive endocrine-mediated perturbations
IVTH0.000005 M 0.000005 MDecreased progesterone levelsReproductive endocrine-mediated perturbations
IVTH0.000005 M 0.000005 MDecreased estradiol levelsReproductive endocrine-mediated perturbations
IVTH0.000005 M 0.000005 MDecreased estrone levelsReproductive endocrine-mediated perturbations
IVTH0.000005 M 0.000005 MDecreased androstenedione levelsReproductive endocrine-mediated perturbations

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.