| Literature identifier | Study type | Test dosage | Effective dosage | Endocrine-mediated endpoints | Systems-level perturbations |
|---|---|---|---|---|---|
| PMID:15597897 | IVTH | 0.00001 M | 0.00001 M | Occurrence of mammary gland tumor | Endocrine-mediated cancer;Reproductive endocrine-mediated perturbations |
| PMID:15620428 | IVR | 0.087 M | 0.087 M | Affects catecholamine biosynthesis | Metabolic endocrine-mediated perturbations;Neurological endocrine-mediated perturbations |
| IVR | 0.087 M | 0.087 M | Affects social behavior | Neurological endocrine-mediated perturbations | |
| PMID:17983274 | IVTH | 0.000000001 - 0.0001 M | 0.000001 M | Cancer phenotype | Endocrine-mediated cancer |
| PMID:18174953 | IVTH | 0.00000001 - 0.0001 M | 0.0000001 - 0.00001 M | Affects steroidogenesis | Reproductive endocrine-mediated perturbations |
| PMID:20197112 | IVTH | 0.00000000001 - 0.0000001 M | 0.0000000001 - 0.00000001 M | Induced migration capability of tumor cells | Endocrine-mediated cancer |
| PMID:20668312 | IVR | 100 mg/L | 100 mg/L | Occurrence of mammary gland tumor | Endocrine-mediated cancer;Reproductive endocrine-mediated perturbations |
| IVR | 10 mg/L | - | No significant effects observed | - | |
| IVR | 1000 mg/L | 1000 mg/L | Occurrence of mammary gland tumor | Endocrine-mediated cancer;Reproductive endocrine-mediated perturbations | |
| IVR | 1000 mg/L | 1000 mg/L | Decreased uterine weights | Reproductive endocrine-mediated perturbations | |
| PMID:29935216 | IVR | 12.5 mg/kg | 12.5 mg/kg | Affects calcium signaling | Metabolic endocrine-mediated perturbations |
| IVR | 12.5 mg/kg | 12.5 mg/kg | Elevated glucose levels | Metabolic endocrine-mediated perturbations | |
| IVR | 12.5 mg/kg | 12.5 mg/kg | Elevated insulin levels | Metabolic endocrine-mediated perturbations |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.