| Literature identifier | Study type | Test dosage | Effective dosage | Endocrine-mediated endpoints | Systems-level perturbations |
|---|---|---|---|---|---|
| PMID:23470461 | IVR | 200 mg/L | 200 mg/L | Affects folliculogenesis | Reproductive endocrine-mediated perturbations |
| IVR | 200 mg/L | 200 mg/L | Follicular atresia | Reproductive endocrine-mediated perturbations | |
| IVR | 200 mg/L | 200 mg/L | Decreased testosterone levels | Reproductive endocrine-mediated perturbations | |
| IVR | 200 mg/L | 200 mg/L | Increased FSH levels | Reproductive endocrine-mediated perturbations | |
| IVR | 200 mg/L | 200 mg/L | Decreased estradiol levels | Reproductive endocrine-mediated perturbations | |
| IVR | 200 mg/L | 200 mg/L | Affects the biochemical composition of ovary | Reproductive endocrine-mediated perturbations | |
| IVR | 200 mg/L | 200 mg/L | Decreased progesterone levels | Reproductive endocrine-mediated perturbations | |
| IVR | 200 mg/L | 200 mg/L | Oxidative stress in liver | Hepatic endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Decreased progesterone levels | Reproductive endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Decreased testosterone levels | Reproductive endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Affects folliculogenesis | Reproductive endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Decreased estradiol levels | Reproductive endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Oxidative stress in liver | Hepatic endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Affects the biochemical composition of ovary | Reproductive endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Increased FSH levels | Reproductive endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Follicular atresia | Reproductive endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Decreased progesterone levels | Reproductive endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Decreased estradiol levels | Reproductive endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Affects folliculogenesis | Reproductive endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Increased FSH levels | Reproductive endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Affects the biochemical composition of ovary | Reproductive endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Oxidative stress in liver | Hepatic endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Follicular atresia | Reproductive endocrine-medi | |
| IVR | 50 mg/L | 50 mg/L | Decreased testosterone levels | ||
| PMID:28911802 | IVR | 200 mg/L | 200 mg/L | Elevated glucose levels | Metabolic endocrine-mediated perturbations |
| IVR | 200 mg/L | 200 mg/L | Elevated insulin levels | Metabolic endocrine-mediated perturbations | |
| IVR | 200 mg/L | 200 mg/L | Reduced glucose levels | Metabolic endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Elevated glucose levels | Metabolic endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Reduced glucose levels | Metabolic endocrine-mediated perturbations | |
| IVR | 100 mg/L | 100 mg/L | Elevated insulin levels | Metabolic endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Reduced glucose levels | Metabolic endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Elevated insulin levels | Metabolic endocrine-mediated perturbations | |
| IVR | 50 mg/L | 50 mg/L | Elevated glucose levels | Metabolic endocrine-mediated perturbations |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.