N,N'-Methylene-bis(2-amino-5-sulfhydryl-1,3,4-thiadiazole)


Literature identifierStudy typeTest dosageEffective dosageEndocrine-mediated endpointsSystems-level perturbations
PMID:19070471IVR20 mg/kg/day 20 mg/kg/dayHyperplasia in thyroid glandMetabolic endocrine-mediated perturbations
IVR20 mg/kg/day 20 mg/kg/dayHypertrophy in thyroid glandMetabolic endocrine-mediated perturbations
IVR40 mg/kg/day 40 mg/kg/dayIncreased ovarian weightsReproductive endocrine-mediated perturbations
IVR40 mg/kg/day 40 mg/kg/dayDecrease in T3 levelsMetabolic endocrine-mediated perturbations
IVR40 mg/kg/day 40 mg/kg/dayHyperplasia in thyroid glandMetabolic endocrine-mediated perturbations
IVR40 mg/kg/day 40 mg/kg/dayDecrease in T4 levelsMetabolic endocrine-mediated perturbations
IVR40 mg/kg/day 40 mg/kg/dayIncrease in TSH levelsMetabolic endocrine-mediated perturbations
IVR40 mg/kg/day 40 mg/kg/dayIncreased weights of thyroid glandMetabolic endocrine-mediated perturbations
IVR40 mg/kg/day 40 mg/kg/dayHypertrophy in thyroid glandMetabolic endocrine-mediated perturbations
IVR10 mg/kg/day 10 mg/kg/dayHyperplasia in thyroid glandMetabolic endocrine-mediated perturbations

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