| Literature identifier | Study type | Test dosage | Effective dosage | Endocrine-mediated endpoints | Systems-level perturbations |
|---|---|---|---|---|---|
| PMID:18850357 | IVR | 500 mg/kg | 500 mg/kg | Alterations in splenocytes population | Immunological endocrine-mediated perturbations |
| IVR | 500 mg/kg | 500 mg/kg | Affects litter size | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/kg | 500 mg/kg | Reduced sperm counts | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/kg | 500 mg/kg | Affects survival of germ cells | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/kg | 500 mg/kg | Pregnancy complications | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/kg | 500 mg/kg | Decreased testis weights | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/kg | 500 mg/kg | Decreased weights of epididymis | Reproductive endocrine-mediated perturbations | |
| IVR | 500 mg/kg | 500 mg/kg | Affects survival of live fetus | Reproductive endocrine-mediated perturbations | |
| IVR | 20 mg/kg | - | No significant effects observed | - | |
| IVR | 100 mg/kg | - | No significant effects observed | - | |
| PMID:2606405 | IVR | 0.7 % | 0.7 % | Changes in haemocrit values | Immunological endocrine-mediated perturbations |
| IVR | 0.7 % | 0.7 % | Affects skeletal development | Developmental endocrine-mediated perturbations | |
| IVR | 0.07 % | - | No significant effects observed | - | |
| IVR | 0.2 % | 0.2 % | Affects skeletal development | Developmental endocrine-mediated perturbations |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.