Methyl methacrylate

• Identification
• Experimental evidence
• Physicochemical properties
• ADMET properties
• Chemical-gene interaction
• Descriptors
• Presence in chemical regulation or guideline
• Presence in human biospecimen

Literature identifier	Study type	Test dosage	Effective dosage	Endocrine-mediated endpoints	Systems-level perturbations
PMID:12748739	IVR	250 mg/L	250 mg/L	Changes in brain morphology	Neurological endocrine-mediated perturbations
	IVR	4450 mg/L	-	No significant effects observed	-
	IVR	3000 mg/L	-	No significant effects observed	-
	IVR	1190 mg/L	-	No significant effects observed	-
	IVR	2220 mg/L	-	No significant effects observed	-
	IVR	4060 mg/L	-	No significant effects observed	-
	IVR	75 mg/L	-	No significant effects observed	-
	IVR	2000 mg/L	-	No significant effects observed	-
	IVR	1000 mg/L	1000 mg/L	Hepatocellular carcinoma	Endocrine-mediated cancer;Hepatic endocrine-mediated perturbations
	IVR	2160 mg/L	-	No significant effects observed	-
	IVR	1000 mg/L	1000 mg/L	Changes in brain morphology	Neurological endocrine-mediated perturbations
	IVR	125 mg/L	-	No significant effects observed	-
	IVR	4630 mg/L	-	No significant effects observed	-
	IVR	5000 mg/L	-	No significant effects observed	-
	IVR	16000 mg/L	-	No significant effects observed	-
	IVR	500 mg/L	500 mg/L	Hepatocellular carcinoma	Endocrine-mediated cancer;Hepatic endocrine-mediated perturbations

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We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.