Toluene-2,4-diamine


Literature identifierStudy typeTest dosageEffective dosageEndocrine-mediated endpointsSystems-level perturbations
PMID:3199457IVR0.06 % 0.06 %Increased testis weightsReproductive endocrine-mediated perturbations
IVR0.06 % 0.06 %Reduced sperm countsReproductive endocrine-mediated perturbations
IVR0.06 % 0.06 %Increased weights of epididymisReproductive endocrine-mediated perturbations
IVR0.03 % 0.03 %Increased weights of epididymisReproductive endocrine-mediated perturbations
IVR0.03 % 0.03 %Reduced sperm countsReproductive endocrine-mediated perturbations
IVR0.03 % 0.03 %Increased testis weightsReproductive endocrine-mediated perturbations
PMID:3937900IVR0.03 % 0.03 %Decreased weights of epididymisReproductive endocrine-mediated perturbations
IVR0.03 % 0.03 %Reduced sperm countsReproductive endocrine-mediated perturbations
IVR0.03 % 0.03 %Decreased weights of seminal vesiclesReproductive endocrine-mediated perturbations
IVR0.03 % 0.03 %Increased testosterone levelsReproductive endocrine-mediated perturbations
IVR0.03 % 0.03 %Increased LH levelsReproductive endocrine-mediated perturbations
IVR0.01 % -No significant effects observed-
PMID:4093994IVR15 mg/kg/day 15 mg/kg/dayAffects fertilityReproductive endocrine-mediated perturbations
IVR5 mg/kg/day -No significant effects observed-

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