| Literature identifier | Study type | Test dosage | Effective dosage | Endocrine-mediated endpoints | Systems-level perturbations |
|---|---|---|---|---|---|
| PMID:12579207 | IVR | 750 mg/L | 750 mg/L | Occurrence of mammary gland tumor | Endocrine-mediated cancer;Reproductive endocrine-mediated perturbations |
| IVR | 750 mg/L | 750 mg/L | Hyperplasia in pituitary gland | Neurological endocrine-mediated perturbations | |
| IVR | 750 mg/L | 750 mg/L | Changes in haemocrit values | Immunological endocrine-mediated perturbations | |
| IVR | 750 mg/L | 750 mg/L | Hyperplasia in testis | Reproductive endocrine-mediated perturbations | |
| IVR | 750 mg/L | 750 mg/L | Hepatocellular carcinoma | Endocrine-mediated cancer;Hepatic endocrine-mediated perturbations | |
| IVR | 750 mg/L | 750 mg/L | Affects testicular morphology | Reproductive endocrine-mediated perturbations | |
| IVR | 750 mg/L | 750 mg/L | Changes in testicular morphology | Reproductive endocrine-mediated perturbations | |
| IVR | 750 mg/L | 750 mg/L | Affects morphology of hepatocytes | Hepatic endocrine-mediated perturbations | |
| IVR | 750 mg/L | 750 mg/L | Hyperplasia in thyroid gland | Metabolic endocrine-mediated perturbations | |
| IVR | 250 mg/L | 250 mg/L | Hyperplasia in pituitary gland | Neurological endocrine-mediated perturbations | |
| IVR | 75 mg/L | - | No significant effects observed | - |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.