4-Chloroaniline

• Identification
• Experimental evidence
• Physicochemical properties
• ADMET properties
• Chemical-gene interaction
• Descriptors
• Presence in chemical regulation or guideline
• Presence in human biospecimen

Literature identifier	Study type	Test dosage	Effective dosage	Endocrine-mediated endpoints	Systems-level perturbations
PMID:12704433	IVR	60 mg/kg	60 mg/kg	Changes in haemocrit values	Immunological endocrine-mediated perturbations
	IVR	40 mg/kg	40 mg/kg	Hyperplasia of bone marrow	Immunological endocrine-mediated perturbations
	IVR	40 mg/kg	40 mg/kg	Changes in white blood cell (WBC) populations	Immunological endocrine-mediated perturbations
	IVR	40 mg/kg	40 mg/kg	Changes in haemocrit values	Immunological endocrine-mediated perturbations
	IVR	40 mg/kg	40 mg/kg	Affects hematopoiesis of liver	Hepatic endocrine-mediated perturbations;Immunological endocrine-mediated perturbations
	IVR	40 mg/kg	40 mg/kg	Affects hematopoiesis of spleen	Immunological endocrine-mediated perturbations
	IVR	25 mg/kg	25 mg/kg	Affects spleen morphology	Immunological endocrine-mediated perturbations
	IVR	10 mg/kg	10 mg/kg	Changes in haemocrit values	Immunological endocrine-mediated perturbations
	IVR	10 mg/kg	10 mg/kg	Hyperplasia of bone marrow	Immunological endocrine-mediated perturbations
	IVR	10 mg/kg	10 mg/kg	Affects hematopoiesis of spleen	Immunological endocrine-mediated perturbations
	IVR	10 mg/kg	10 mg/kg	Affects hematopoiesis of liver	Hepatic endocrine-mediated perturbations;Immunological endocrine-mediated perturbations
	IVR	50 mg/kg	50 mg/kg	Affects spleen morphology	Immunological endocrine-mediated perturbations
	IVR	6 mg/kg	6 mg/kg	Changes in adrenal gland morphology	Metabolic endocrine-mediated perturbations
	IVR	15 mg/kg	15 mg/kg	Changes in haemocrit values	Immunological endocrine-mediated perturbations
	IVR	2 mg/kg	2 mg/kg	Changes in adrenal gland morphology	Metabolic endocrine-mediated perturbations
	IVR	120 mg/kg	120 mg/kg	Changes in haemocrit values	Immunological endocrine-mediated perturbations
	IVR	18 mg/kg	18 mg/kg	Changes in adrenal gland morphology	Metabolic endocrine-mediated perturbations
	IVR	20 mg/kg	20 mg/kg	Affects hematopoiesis of liver	Hepatic endocrine-mediated perturbations;Immunological endocrine-mediated perturbations
	IVR	20 mg/kg	20 mg/kg	Changes in haemocrit values	Immunological endocrine-mediated perturbations
	IVR	20 mg/kg	20 mg/kg	Affects hematopoiesis of spleen	Immunological endocr
	IVR	0.3 mg/kg	0.3 mg/kg	Changes in haemocrit values
	IVR	20 mg/kg	20 mg/kg	Hyperplasia of bone marrow
	IVR	7.5 mg/kg	7.5 mg/kg	Changes in haemocrit values
	IVR	200 mg/kg	-	No significant effects observed
	IVR	400 mg/kg	-	No significant effects observed
	IVR	80 mg/kg	80 mg/kg	Affects hematopoiesis of spleen
	IVR	80 mg/kg	80 mg/kg	Hyperplasia of bone marrow
	IVR	80 mg/kg	80 mg/kg	Decreased brain weights
	IVR	80 mg/kg	80 mg/kg	Changes in haemocrit values
	IVR	80 mg/kg	80 mg/kg	Affects hematopoiesis of liver
	IVR	30 mg/kg	30 mg/kg	Changes in haemocrit values
	IVR	100 mg/kg	100 mg/kg	Affects spleen morphology
	IVR	5 mg/kg	5 mg/kg	Hyperplasia of bone marrow
	IVR	5 mg/kg	5 mg/kg	Affects hematopoiesis of liver
	IVR	5 mg/kg	5 mg/kg	Change
	IVR	5 mg/kg	5 mg/kg

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