2,4-Dichlorophenol


Literature identifierStudy typeTest dosageEffective dosageEndocrine-mediated endpointsSystems-level perturbations
PMID:16641544IVR500 mg/L -No significant effects observed-
IVR8000 mg/L 8000 mg/LIncreased uterine weights in offspringDevelopmental endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
IVR8000 mg/L 8000 mg/LChanges in morphology of thyroid glandMetabolic endocrine-mediated perturbations
IVR2000 mg/L 2000 mg/LIncreased uterine weights in offspringDevelopmental endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
PMID:22155427IVTH1 mg/L 1 mg/LAffects steroidogenesisReproductive endocrine-mediated perturbations
IVTH1 mg/L 1 mg/LDecreased estradiol levelsReproductive endocrine-mediated perturbations
IVTH0.3 mg/L 0.3 mg/LAffects steroidogenesisReproductive endocrine-mediated perturbations
IVTH0.3 mg/L 0.3 mg/LDecreased estradiol levelsReproductive endocrine-mediated perturbations
IVTH0.1 mg/L 0.1 mg/LAffects steroidogenesisReproductive endocrine-mediated perturbations

DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.