| Literature identifier | Study type | Test dosage | Effective dosage | Endocrine-mediated endpoints | Systems-level perturbations |
|---|---|---|---|---|---|
| PMID:11823001 | IVTH | 0.00000001 - 0.0001 M | 0.00000001 - 0.000001 M | Cancer phenotype | Endocrine-mediated cancer |
| PMID:14643963 | IVR | 100 mg/kg/day | 100 mg/kg/day | Increased uterine weights | Reproductive endocrine-mediated perturbations |
| IVR | 300 mg/kg/day | 300 mg/kg/day | Increased uterine weights | Reproductive endocrine-mediated perturbations | |
| IVR | 1000 mg/kg/day | 1000 mg/kg/day | Increased uterine weights | Reproductive endocrine-mediated perturbations | |
| PMID:15458796 | IVR | 0 NA | - | Increased uterine weights | Reproductive endocrine-mediated perturbations |
| PMID:15721882 | IVR | 100 mg/kg/day | - | No significant effects observed | - |
| IVR | 250 mg/kg/day | - | No significant effects observed | - | |
| IVR | 625 mg/kg/day | 625 mg/kg/day | Increased uterine weights | Reproductive endocrine-mediated perturbations | |
| PMID:23328252 | IVTH | 0.000000001 - 0.00001 M | 0.00000001 - 0.00001 M | Cancer phenotype | Endocrine-mediated cancer |
| IVR | 200 mg/kg/day | 200 mg/kg/day | Cancer phenotype | Endocrine-mediated cancer | |
| PMID:25682003 | IVTH | 0.00000001 - 0.00001 M | 0.00000001 - 0.00001 M | Cancer phenotype | Endocrine-mediated cancer |
| PMID:25849766 | IVTH | 0.000000001 - 0.000001 M | 0.0000001 - 0.00001 M | Cancer phenotype | Endocrine-mediated cancer |
| IVTH | 0.000000001 - 0.000001 M | 0.0000001 - 0.00001 M | Induce cancer metastasis | Endocrine-mediated cancer | |
| PMID:27145024 | IVTH | 0.000001 M | 0.000001 M | Induce cancer metastasis | Endocrine-mediated cancer |
| PMID:28990245 | IVTH | 0.00001 M | 0.00001 M | Induced migration capability of tumor cells | Endocrine-mediated cancer |
| IVTH | 0.0000001 M | 0.0000001 M | Induced migration capability of tumor cells | Endocrine-mediated cancer |
We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.