Zinc chloride

• Identification
• Experimental evidence
• Physicochemical properties
• ADMET properties
• Descriptors
• Chemical-gene interaction
• Chemical-phenotype interaction
• Chemical-disease association
• ToxCast endpoints
• Associated AOPs
• Presence in consumer products
• Presence in chemical regulation or guideline
• Presence in human biospecimen

Literature identifier	Study type	Test dosage	Effective dosage	Endocrine-mediated endpoints	Systems-level perturbations
PMID:17474020	IVR	7.5 mg/kg/day	7.5 mg/kg/day	Decreased spleen weights in offspring	Developmental endocrine-mediated perturbations;Immunological endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased weights of seminal vesicles in offspring	Developmental endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Increased weights of adrenal gland in offspring	Developmental endocrine-mediated perturbations;Metabolic endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased brain weights in offspring	Developmental endocrine-mediated perturbations;Neurological endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased spleen weights in offspring	Developmental endocrine-mediated perturbations;Immunological endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased weights of seminal vesicles	Reproductive endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased brain weights	Neurological endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased liver weights	Hepatic endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Increased prostate weights in offspring	Developmental endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased liver weights in offspring	Developmental endocrine-mediated perturbations;Hepatic endocrine-mediated perturbations
	IVR	7.5 mg/kg/day	7.5 mg/kg/day	Decreased liver weights	Hepatic endocrine-mediated perturbations
	IVR	7.5 mg/kg/day	7.5 mg/kg/day	Decreased brain weights	Neurological endocrine-mediated perturbations
	IVR	15 mg/kg/day	15 mg/kg/day	Decreased testis weights in offspring	Developmental endocrine-mediated perturbations;Reproductive endocrine-mediated perturbations
	IVR	30 mg/kg/day	30 mg/kg/day	Increased prostate weights in offspring	Developmental endocrine-mediated perturbations;Reproductive endocr
	IVR	7.5 mg/kg/day	7.5 mg/kg/day	Increased prostate weights in offspring
	IVR	30 mg/kg/day	30 mg/kg/day	Decreased brain weights
	IVR	30 mg/kg/day	30 mg/kg/day	Decreased spleen weights
	IVR	30 mg/kg/day	30 mg/kg/day	Decreased liver weights
	IVR	30 mg/kg/day	30 mg/kg/day	Affects fertility
	IVR	30 mg/kg/day	30 mg/kg/day	Decreased spleen weights in offspring
	IVR	30 mg/kg/day	30 mg/kg/day	Decreased brain weights in offspring
	IVR	30 mg/kg/day	30 mg/kg/day	Decreased weights of seminal vesicles

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