2-Benzyl-2-(dimethylamino)-1-(4-(morpholin-4-yl)phenyl)butan-1-one

• Identification
• Experimental evidence
• Physicochemical properties
• ADMET properties
• Descriptors
• Chemical-gene interaction
• Chemical-phenotype interaction
• Chemical-disease association
• ToxCast endpoints
• Associated AOPs
• Presence in consumer products
• Presence in chemical regulation or guideline
• Presence in human biospecimen

Literature identifier	Study type	Test dosage	Effective dosage	Endocrine-mediated endpoints	Systems-level perturbations
PMID:37797914	IVR	2 mg/kg/day	2 mg/kg/day	Decreased testis weights	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Decreased weights of seminal vesicles	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Increased LH levels	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Changes in morphology of seminal vesicles	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Increased FSH levels	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Increased weights of seminal vesicles	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Affects steroidogenesis	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Reduced sperm counts	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Affects testicular morphology	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Decreased testosterone levels	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Oxidative stress in testis	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Affects sperm motility	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Abnormal sperm morphology	Reproductive endocrine-mediated perturbations
	IVR	2 mg/kg/day	2 mg/kg/day	Increased gonadotropin-releasing hormone (GnRH) levels	Reproductive endocrine-mediated perturbations

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