IMPPAT | IMPPAT: Indian Medicinal Plants, Phytochemistry And Therapeutics

Bioactivity information

Target name	Target organism	UniProt identifier	EC50	IC50	Kd	Ki	Source
Mus musculus	Mus musculus			= 200.0 nM			NPASS
Polyphenol oxidase 2	Agaricus bisporus	O42713		100000 nM			BindingDB
Polymerase acidic protein	InflueA virus (strain A/Puerto Rico/8/1934 H1N1)	P03433	>250000 nM				BindingDB
Polymerase acidic protein	InflueA virus (A/Puerto Rico/8/1934(H1N1))	P03433	> 250000.0 nM				NPASS
NON-PROTEIN TARGET				= 5000000.0 nM			NPASS
Meloidogyne incognita	Meloidogyne incognita		= 379.0 ug.mL-1				NPASS
HEK293	Homo sapiens			> 15000000.0 nM			NPASS
MCF7	Homo sapiens			> 100000.0 nM			NPASS
High mobility group protein B1	Homo sapiens	P09429			1000 nM\|= 1000.0 nM		BindingDB, NPASS
HT-29	Homo sapiens			> 100000.0 nM			NPASS
Prolyl 4-hydroxylase subunit alpha-1	Gallus gallus	P16924				2300000 nM	BindingDB
DU-145	Homo sapiens			> 100000.0 nM			NPASS
Cystathionine gamma-lyase	Homo sapiens	P32929		>200000 nM\|> 200000.0 nM			BindingDB, NPASS
Cyclooxygenase-2	Homo sapiens	P35354		> 40000.0 nM			NPASS
Matrix metalloproteinase 3	Homo sapiens	P08254			> 25000000.0 nM		NPASS
Prostaglandin G/H synthase 1	Homo sapiens	P23219		500000 nM\|>40000 nM		>10000 nM	BindingDB
Serum albumin	Homo sapiens	P02768				= 5888436553555.88 nM	NPASS
Protein-tyrosine phosphatase 1B	Homo sapiens	P18031				= 19400000.0 nM	NPASS
Cyclooxygenase-1	Homo sapiens	P23219		= 500000.0 nM\|> 40000.0 nM			NPASS
Xanthine dehydrogenase	Bos taurus	P80457				= 100000000.0 nM	NPASS
Ubiquitin-like domain-containing CTD phosphatase 1	Homo sapiens	Q8WVY7		66000000 nM\|= 66000000.0 nM			BindingDB, NPASS
Tyrosine-protein phosphatase yopH	Yersipseudotuberculosis serotype I (strain IP32953)	P08538				= 1000000.0 nM	NPASS
Xanthine dehydrogenase/oxidase	Bos taurus	P80457				100000000 nM	BindingDB
Tyrosinase	Agaricus bisporus	O42713		= 100000.0 nM			NPASS
Prostaglandin G/H synthase 2	Homo sapiens	P35354		>40000 nM		>10000 nM	BindingDB
Stromelysin-1	Homo sapiens	P08254			>25000000 nM		BindingDB
Solute carrier family 22 member 6	Rattus norvegicus	O35956				1000000 nM\|341000 nM\|= 1000000.0 nM\|= 341000.0 nM	BindingDB, NPASS
Solute carrier family 22 member 6	Mus musculus	Q8VC69				145000 nM\|= 144543.98 nM\|= 145000.0 nM	BindingDB, NPASS
Solute carrier family 22 member 6	Homo sapiens	Q4U2R8		280000 nM\|= 280000.0 nM			BindingDB, NPASS
Solute carrier family 22 member 20	Mus musculus	Q80UJ1				44000 nM\|= 43651.58 nM\|= 44000.0 nM	BindingDB, NPASS
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2			> 20000.0 nM\|> 19952.62 nM			NPASS
Protein-tyrosine-phosphatase	Yersipestis					1000000 nM	BindingDB
Solute carrier family 22 member 8	Homo sapiens	Q8TCC7				1020000 nM\|= 1020000.0 nM	BindingDB, NPASS
Carbonic anhydrase XIV	Homo sapiens	Q9ULX7				= 49800.0 nM	NPASS
Tyrosine-protein phosphatase non-receptor type 1	Homo sapiens	P18031				19400000 nM	BindingDB
Carbonic anhydrase XII	Homo sapiens	O43570				= 8800.0 nM	NPASS
Carbonic anhydrase 13	Mus musculus	Q9D6N1				67000 nM	BindingDB
Carbonic anhydrase 12	Homo sapiens	O43570				8800 nM	BindingDB
Carbonic anhydrase 1	Homo sapiens	P00915		560000 nM		9900 nM\|620000 nM\|9920 nM	BindingDB
Carbonic anhydrase	Dicentrarchus labrax	Q2PCB5				= 324000.0 nM	NPASS
Carbonic anhydrase	Dicentrarchus labrax					324000 nM	BindingDB
Bile salt export pump	Rattus norvegicus	O70127		>1000000 nM\|> 1000000.0 nM			BindingDB, NPASS
Carbonic anhydrase 14	Homo sapiens	Q9ULX7				49800 nM	BindingDB
Bile salt export pump	Homo sapiens	O95342		>1000000 nM\|> 1000000.0 nM			BindingDB, NPASS
Amyloid-beta precursor protein	Homo sapiens	P05067				>1800 nM	BindingDB
Aldose reductase	Homo sapiens	P15121		> 1000000.0 nM			NPASS
Aldo-keto reductase family 1 member B1	Homo sapiens	P15121		>1000000 nM			BindingDB
Albumin	Homo sapiens	P02768				5880 nM	BindingDB
Acetylcholinesterase	Homo sapiens	P22303		346000 nM\|= 346000.0 nM			BindingDB, NPASS
Carbonic anhydrase XIII	Mus musculus	Q9D6N1				= 67000.0 nM	NPASS
Beta amyloid A4 protein	Homo sapiens	P05067				> 1800.0 nM	NPASS
Carbonic anhydrase 15	Mus musculus	Q99N23				7200 nM\|= 7200.0 nM	BindingDB, NPASS
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	Bos taurus	P08487		= 120.63 ug.mL-1			NPASS
Carbonic anhydrase 3	Homo sapiens	P07451				885000 nM	BindingDB
Carbonic anhydrase VII	Homo sapiens	P43166				= 82100.0 nM	NPASS
Carbonic anhydrase VI	Homo sapiens	P23280				= 11900.0 nM\|= 2320000.0 nM	NPASS
Carbonic anhydrase VB	Homo sapiens	Q9Y2D0				= 355000.0 nM	NPASS
Carbonic anhydrase VA	Homo sapiens	P35218				= 678000.0 nM	NPASS
Carbonic anhydrase 2	Homo sapiens	P00918		680000 nM		7100 nM\|740000 nM\|7120 nM	BindingDB
Carbonic anhydrase IV	Homo sapiens	P22748				= 11100.0 nM	NPASS
Carbonic anhydrase III	Homo sapiens	P07451				= 885000.0 nM	NPASS
Carbonic anhydrase IX	Homo sapiens	Q16790				= 78700.0 nM	NPASS
Carbonic anhydrase I	Homo sapiens	P00915		= 560000.0 nM		= 9920.0 nM\|= 620000.0 nM\|= 9900.0 nM	NPASS
Carbonic anhydrase 9	Homo sapiens	Q16790				78700 nM	BindingDB
Carbonic anhydrase 7	Homo sapiens	P43166				82100 nM	BindingDB
Carbonic anhydrase 6	Homo sapiens	P23280				11900 nM\|2320000 nM	BindingDB
Carbonic anhydrase 5B, mitochondrial	Homo sapiens	Q9Y2D0				355000 nM	BindingDB
Carbonic anhydrase 5A, mitochondrial	Homo sapiens	P35218				678000 nM	BindingDB
Carbonic anhydrase 4	Homo sapiens	P22748				11100 nM	BindingDB
Carbonic anhydrase II	Homo sapiens	P00918		= 680000.0 nM		= 7120.0 nM\|= 740000.0 nM\|= 7100.0 nM	NPASS

a curated database

IMPPAT Phytochemical information:
Salicylic acid

Bioactivity information

IMPPAT Phytochemical information: Salicylic acid

Bioactivity information

IMPPAT Phytochemical information:
Salicylic acid