IMPPAT Phytochemical information: 
Salicylic acid

Salicylic acid
Clinical trials
Public title (as per ICTRP)Scientific title (as per ICTRP)Trial identifier
The long-term effectiveness of 40% salicylic acid plasters on cornsThe long-term effectiveness of 40% salicylic acid plasters on corns: a prospective pragmatic parallel-group randomised controlled trialISRCTN13166839
Efficacy Study of the Combination Mometasone + Salicylic Acid in Patients With PsoriasisCLINICAL ASSESSMENT OF THE EFFECTIVENESS OF ASSOCIATION MONETASONE FUROATE 0.1% SALICYLIC ACID AND 5% FOR SUBMISSION OF OINTMENT TOPICAL DERMATOLOGICAL USE OF LABORATORY Glenmark Pharmaceuticals Ltd, IN PATIENTS WITH PSORIASIS.NCT01229085
A study to compare efficacy of isotretinoin and salicylic acid plus mandelic acid peel versus isotretinoin alone in the treatment of acne tardaA Randomized prospective study comparing low dose isotretinoin alone with combination of low dose isotretinoin and salicylic acid plus mandelic acid peel in the treatment of acne tardaCTRI/2020/08/027055
Efficacy and safety of Broda 30% supramolecular salicylic acid in the treatment of severe acneEfficacy and safety of Broda 30% supramolecular salicylic acid in the treatment of severe acneChiCTR2100042950
Silymarin Cream Versus Salicylic Acid in Treatment of Acne VulgarisTopical Silymarin Cream Versus Salicylic Acid Peeling in Treatment of Acne Vulgaris: Split Face StudyNCT04490967
Efficacy and safety of 30% supramolecular salicylic acid in the treatment of rosaceaEfficacy and safety of 30% supramolecular salicylic acid in the treatment of rosacea: A Prospective Randomized Control TrialChiCTR2000029833
The effect of intense pulsed light combined with supramolecular salicylic acid on post-adolescene acneThe effect of intense pulsed light combined with supramolecular salicylic acid on post-adolescene acneChiCTR1900024848
Comparative study for salicylic acid vs glycolic acid in the treatment of mild-to-moderate acne vulgarisComparative study for salicylic acid vs glycolic acid in the treatment of mild-to-moderate acne vulgaris: a prospective, randomized, split-face trialChiCTR1800018343
To Evaluate Whether Acetyl Salicylic Acid (Aspirin), the Combination of Aspirin and Clopidogrel and Darexaban (YM150) Interact in Their EffectsA Randomized, Open-label, Two-period Crossover Study in Healthy Male Subjects to Evaluate the Pharmacodynamic Effect of Darexaban (YM150) on Acetyl Salicylic Acid (ASA) and of Darexaban on the Combination of ASA and Clopidogrel at Steady StateNCT01409616
Prevention of acute coronary syndrome by aspirin in patients with breast cancer.The reduction by acetyl salicylic acid of death rate due to acute coronary syndrome in patients with breast cancer.CTRI/2014/12/005235
Effect of Neem Extract, Propylene Glycol and Salicylic Acid Combination in the Treatment of Arsenical Palmar KeratosisRandomized, Single Blind, Placebo Controlled Clinical Trial to See the Effect of Combination of Neem, Propylene Glycol and Salicylic Acid in the Treatment of Arsenical Palmar KeratosisNCT02352987
Treatment of Melasma With Glycolic Acid-Salicylic Acid Peel Versus Glycolic Acid PeelComparing the Efficacy and Safety of Combined Glycolic Acid and Salicylic Acid Peel Versus Glycolic Acid Peel Alone in the Treatment of Melasma: A Split Face StudyNCT02812719
A 3 month clinical trial of herbal medicine combination intended for topical application in patients with leg symptoms complaints due to chronic venous insufficiency: a double-blind randomized controlled trialHerbal medicine combination containing acetyl salicylic acid and asiaticoside plus acemannan in topical gel formulation for chronic venous insufficiency: a 3 month double-blind randomized placebo-controlled trial among Thai patients diagnosed as mild-to-moderate chronic venous insufficiencyISRCTN54360155
Compared the effect of salicylic acid and Cryotherapy in the treatment of warts.Comparison of the effects of salicylic acid solutions versus Cryotherapy for the treatment of Extra genital wart on patients referred to the Farshchian hospital.IRCT2016052328008N1
Climatotherapy Versus Topical Combination of Corticosteroids and Salicylic Acid in Treatment of PsoriasisClimatotherapy at Red Sea - Hurghada Versus Topical Combination of Corticosteroids and Salicylic Acid in Treatment of PsoriasisNCT03156062
A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of MelasmaA Pilot Study Comparing the Efficacy of Glycolic Acid Peels Vs. Salicylic Acid Peels for the Treatment of Melasma: a Randomized Control TrialNCT01976286
Parallel Group Trial to Evaluate the Efficacy and Safety of Loion® Compared to 10% Salicylic Acid in Patients With Chronic Psoriasis CapitisA Single-centre Randomised, Active-controlled, Observer-blinded, Parallel Group Trial to Evaluate the Efficacy and Safety of a Topical Dimeticone Formulation (Loion®) Compared to 10% Salicylic Acid in the Removal of Scaling in Patients With Chronic Psoriasis CapitisNCT01914627
Comparing one new treatment calcipotriol cream with old coaltar ointment in patients with chronic plaque psoriasisCOMPARATIVE EVALUATION OF TOPICAL CALCIPOTRIOL VS. COAL TAR AND SALICYLIC ACID OINTMENT IN CHRONIC PLAQUE PSORIASISCTRI/2013/02/003384
Efficiency and tolerability of 30% new supramolecular salicylic acid for rosaceaEfficacy and skin tolerability of the addition of 30% new supramolecular salicylic acid to Minocycline for erythematotelangiectatic and papulopustular rosacea:A split-face studyChiCTR-OOH-17012560
Comparison of Myrtus Communis L. and Descurainia Sophia L. versus salicylic acid in the treatment of wartComparison the efficacy of Myrtus Communis L. and Descurainia Sophia L. as a method of traditional medicine versus salicylic acid in the treatment of wartIRCT2012092710947N1
Treatment of acne vulgaris with salicylic acid peelEfficacy and tolerability of the 30% new supramolecular salicylic acid peel in the treatment of acne vulgarisChiCTR1800016025
Effect of combined topical solution 2% salicylic acid and erythromycin 4% with erythromycin 4% topical solution in the treatment of mild to moderate acne vulgarisComparison???? of efficacy of topical combination solution of salicylic acid 2% and erythromycin 4% with topical solution of erythromycin 4% alone in mild to moderate acne vulgaris treatment; double-blinded randomized clinical trialIRCT201010094269N3
To Evaluate Whether Acetyl Salicylic Acid (Aspirin) and Darexaban (YM150) Interact in Their EffectsA Randomized, Open Label, Three-way Crossover Study to Evaluate the Pharmacodynamic Interactions Between Darexaban (YM150)/Darexaban Glucuronide (YM-222714) and Acetyl Salicylic Acid (ASA) in Healthy Male SubjectsNCT01424332
Comparison of use of glycolic acid and salicylic acid peel in acne(pimples).Comparative efficacy of glycolic acid 35% vs salicylic acid 20% peel in acne vulgaris.CTRI/2018/06/014615
A Study Comparing The Efficacy and Safety of Jessner's Solution And Salicylic Acid 30% Chemical Peel and in the Management of Acne Vulgaris and Post Acne HyperpigmentationEfficacy and safety of Jessner’s Solution peel (JS) in comparison with Salicylic Acid 30% peel (SA) in management of patients with acne vulgaris and post acne hyperpigmentation: A randomized, double-blinded, split-face, controlled trialTCTR20190118001
Skin Irritation Test of KETOSOFT Shampoo Containing Salicylic Acid and Ketoconazole Medicated in Healthy Human Volunteers"""Skin lrritation Test of KETOSOFT Shampoo (Salicylic Acid & KetoconazoleMedicated) in Healthy Human Volunteers"""CTRI/2019/07/020122
A Randomised, Double-blind, Double-dummy, Parallel Group, International (Asian), Multicenter, Phase 3 Study to Assess Safety and Efficacy of AZD6140 on Top of Low Dose Acetyl Salicylic Acid (ASA) Versus Clopidogrel on Top of Low Dose ASA in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes(ACS) for Whom PCI is PlannedA Randomised, Double-blind, Double-dummy, Parallel Group, International (Asian), Multicenter, Phase 3 Study to Assess Safety and Efficacy of AZD6140 on Top of Low Dose Acetyl Salicylic Acid (ASA) Versus Clopidogrel on Top of Low Dose ASA in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes(ACS) for Whom PCI is PlannedJPRN-jRCT2080221435
A Comparative clinical study on effect of kshara lepa application and salicylic acid on charmakeela(warts)A clinical comparative study on effect of kshara lepa application and salicylic acid on charmakeela(warts)CTRI/2021/03/031820
Clinical efficacy of supramolecular salicylic acid combined with intense pulsed light in the treatment of rosacea and its effect on skin barrier functionClinical efficacy of supramolecular salicylic acid combined with intense pulsed light in the treatment of rosacea and its effect on skin barrier functionChiCTR2500096212
The effects of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid on facial sebum characteristics in oily skin subjects: a pilot studyThe effects of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid on facial sebum characteristics in oily skin subjects: a pilot studyTCTR20210531002
To analyze and evaluate the effects of 20% salicylic acid peel along with oral and topical antifungal therapy versus oral and topical antifungal therapy without 20% salicylic peel in the treatment of ringworm infections.Effectiveness and safety of 20% salicylic acid peel in combination with oral and topical antifungal versus oral and topical antifungal therapy for the treatment of superficial dermatophytosis.CTRI/2023/07/054952
Efficacy and safety of 30% supramolecular salicylic acid in the treatment of acne vulgaris in adolescents aged 12-17 yearsEfficacy and safety of 30% supramolecular salicylic acid in the treatment of acne vulgaris in adolescents aged 12-17 yearsChiCTR2300073469
Effects of supramolecular salicylic acid on the composition, function and metabolism of acne skin microbial floraEffects of supramolecular salicylic acid on the composition, function and metabolism of acne skin microbial floraChiCTR2300073931
Which works better in dermatophytosis - salicylic acid 30% with luliconazole or luliconazole cream alone?Efficacy of luliconazole 1% cream alone vs combination therapy of luliconazole 1% cream with 30% salicylic peel on patients of superficial dermatophytosisCTRI/2023/07/055855
Glycolic Acid Plus Salicylic Acid in Treatment of Plane WartEfficacy of Glycolic Acid 15%Plus Salicylic Acid 2% Gel in Treatment of Plane WartNCT06233019
Efficacy study and safety evaluation clinical trial of red light photodynamic combined with supramolecular salicylic acid in the treatment of moderate to severe acneEfficacy study and safety evaluation clinical trial of red light photodynamic combined with supramolecular salicylic acid in the treatment of moderate to severe acneChiCTR2400079708
Efficacy and Safety of 30% Supramolecular Salicylic Acid Combined With Supramolecular Active Zinc in the Treatment of Malassezia FolliculitisEfficacy and Safety of 30% Supramolecular Salicylic Acid Combined With Supramolecular Active Zinc in the Treatment of Malassezia FolliculitisNCT06307223
Comparative study between efficacy of two combination peels in acne vulgaris grade II and IIIComparative study between efficacy of 18 percent Salicylic acid and 15 percent Azelaic acid combination peel vs 20 percent Salicylic acid and 10 percent Mandelic acid combination peel in Acne vulgaris grade II & III - A Randomized Controlled Trial - NILCTRI/2024/06/069015
Skin Irritation of Mosaic Wellness Hyaluronic Acid Body Wash Mousse and 2percent Salicylic Acid Cleansing BalmA Clinical Study to Evaluate the Skin Irritation Potential of Mosaic Wellness Hyaluronic Acid Body Wash Mousse and 2percent Salicylic Acid Cleansing Balm on Healthy Human Subjects - NILCTRI/2024/07/071474
Efficacy of Home Use of Hyperthermia to Improve Plantar Wart Clearance Rate with Topical Salicylic Acid/5-FU Therapy - A Randomized, Placebo-controlled, Double-blind Clinical TrialEfficacy of Home Use of Hyperthermia to Improve Plantar Wart Clearance Rate with Topical Salicylic Acid/5-FU Therapy - A Randomized, Placebo-controlled, Double-blind Clinical TrialDRKS00034578
A clinical trial to study the regeneration of bone in patients with periodontitis with xenograft and aspirinevaluation of the efficacy of acetyl salicylic acid combined with xenograft for the treatment of periodontal osseous defects: A randomised clinical trial - NILCTRI/2024/09/073707
Anti-acne test of Asaya SerumA consumer study to check anti-acne activity of Asaya 2% Salicylic Acid and 5% Niacinamide Serum - NILCTRI/2024/10/074852
The Efficacy and Mechanisms of Fire Needling and 30% Salicylic Acid in the Treatment of Common AcneThe Efficacy and Mechanisms of Fire Needling Combined with 30% Salicylic Acid in the Treatment of Common AcneChiCTR2400092514
A randomised control experiment comparing the efficacy of traditional treatment for nail thickening issues with customised nail patches containing urea, glycerin, salicylic acid, and biotinEffectiveness of customized nail patches containing Urea, Glycerin, Salicylic acid and Biotin versus conventional treatment in disorders of nail thickening: A randomized control trial - NILCTRI/2024/12/078603
Anti-acne activity of Plum Salicylic Acid Face WashA Clinical Study to Evaluate the Anti-acne activity of Plum Salicylic Acid Face Wash - NILCTRI/2024/12/078638
Clinical trial to study the effect of two chemical peels 30% salicyclic acid and 40% mandelic acid peel in acne vulgarisComparative study of the efficacy of 30% Salicylic and 40% Mandelic acid peels in acne vulgaris :randomized controlled trial in a tertiary care centre,Chengalpattu,Tamilnadu.CTRI/2023/04/051974
Cleaning Activity of Plum Salicylic Acid Face WashA Clinical Study to Evaluate the Cleaning Potential of Plum Salicylic Acid Face Wash On Healthy Human Volunteers - NILCTRI/2025/02/081467
A Randomized Control study To Assess The Efficacy Of topical keratolytics versus keratolytics delivered through iontophoresis in the treatment of wart over soles at a tertiary care centreA Randomized Control Trial To Assess The Efficacy Of 16.7%Salicylic Acid With 16.7%Lactic Acid Iontophoresis Versus Topical 16.7%Salicylic Acid With 16.7%Lactic Acid In The Treatment Of Plantar Verrucae At A Tertiary Care Centre.CTRI/2023/01/049095
Comparison of laser ablation and chemical ablation in facial verruca planaEfficacy and safety of erbium YAG laser vs salicylic acid and lactic acid flexible collodion paint in facial verruca plana: a comparative studyCTRI/2022/12/048379
A comparative study about chemical peel in acneA RANDOMIZED control trial to compare the efficacy and safety of 40% mandelic acid peel with 30% salicylic acid peel in Acne vulgarisCTRI/2021/07/035095
Clincal study to compare the therapeutic effects of two ointments with active substances betamethasone dipropionate and salicylic acid and of one ointment without active substance for patients with chronic stable plaque psoriasisDouble-blind, randomised clinical study comparing efficacy and safety of Betamethasone dipropionate 0.64 mg/g _ Salicylic acid 30 mg/g Ointment (Test) vs. Diprosalic(R) Ointment (Reference) vs. Vehicle in patients with chronic stable plaque psoriasisEUCTR2020-004081-19-DE
A clinical trial to study the effects of a novel combination pimple patch versus conventional topical gel in acne patients.To study the effectiveness of novel combination hydrogel pimple patch containing Azelaic acid, Salicylic acid and Zinc oxide versus conventional topical spot treatment available for the treatment of acne vulgaris : a randomized control trial - NILCTRI/2025/02/080180
The effectiveness of Dorema ammoniacum gum in the treatment of skin wartsEvaluation of the effectiveness of Dorema ammoniacum gum in the treatment of skin warts Compared to salicylic acidIRCT20150721023282N20
Evaluation of efficacy and safety of 30% supramolecular salicylic acid combined with supramolecular active zinc in the treatment of Malassezia FolliculitisEvaluation of efficacy and safety of 30% supramolecular salicylic acid combined with supramolecular active zinc in the treatment of Malassezia FolliculitisChiCTR2100052619
Salicylic acid in acne vulgarisComparison of the effect of 40% salicylic acid versus 30% salicylic acid with and without combination with doxycycline in the treatment of moderate acne vulgaris: a double-blinded, randomized, clinical trialIRCT20211102052949N1
Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne VulgarisEfficacy and Safety of Topical Metformin Emulgel Versus Salicylic Acid Peeling in Treatment of Acne Vulgaris: A Split Face StudyNCT05536193
To evaluate safety of a test product for skin irritationEvaluation of Skin Safety of 1 test product (Luliconazole & Salicylic Acid & Zinc Pyrithione Shampoo) for Primary Skin Irritation Using Skin Irritation Test (Patch Test in Humans)IS 4011:2018 Guidelines.CTRI/2021/03/032171
Comparative Study Between Treatment With Cryotherapy Alone Versus Cryotherapy Plus Salicylic Acid Dressing for Planter WartsComparative Study Between Treatment With Cryotherapy Alone Versus Cryotherapy Plus Salicylic Acid Dressing for Planter WartsNCT05588999
A clinical study protocol to evaluate the efficacy and safety of supramolecular salicylic acid in the treatment of rosaceaEvaluation of efficacy and safety of supramolecular salicylic acid in the treatment of rosaceaChiCTR2200065218
Clinical study of BRODA 2% supramolecular salicylic acid in the treatment of mild to moderate acne vulgarisClinical study of BRODA 2% supramolecular salicylic acid in the treatment of mild to moderate acne vulgarisChiCTR2200065348
Effectiveness of Association Mometasone Furoate 0.1% and Salicylic Acid 5% Compared With Mometasone FuroateCLINICAL EVALUATION OF EFFECTIVENESS OF ASSOCIATION MOMETASONE FUROATE 0.1% AND SALICYLIC ACID 5% COMPARED WITH 0.1% MOMETASONE FUROATE INSULATED TOPICAL USE OF LABORATORY Glenmark Pharmaceuticals Ltd, IN PATIENTS WITH PSORIASIS IN PLATENCT01228656
Clinical study on efficacy and safety of 30% supramolecular salicylic acid combined with 10% niacinamide in the treatment of chloasmaClinical study on efficacy and safety of 30% supramolecular salicylic acid combined with 10% niacinamide in the treatment of chloasma - Clinical study of supramolecular salicylic acid on melasmaChiCTR2200065346
FMRF Combined With 30% SSA in the Treatment of RosaceaEfficacy and Safety Evaluation of Fractional Microneedling Radiofrequency Combined With 30% Supramolecular Salicylic Acid in the Treatment of Refractory Erythrotelangiectatic RosaceaNCT06969300
Treatment of keratosis pilaris with combined salicylic acid, licochalcone A, and isobutylamido thiazolyl resorcinol: A single-blind randomized controlled studyTreatment of keratosis pilaris with combined salicylic acid, licochalcone A, and isobutylamido thiazolyl resorcinol: A single-blind randomized controlled studyTCTR20250401001
A comparative study on fugal disease between conventional treatment and a new treatment of approach using 30 percent salicylic acid peel in patient with fungal diseaseASSESSING THE EFFICACY OF 30 PERCENT SALICYLIC ACID PEEL WITH1 PERCENT TOPICAL LULICONAZOLE FOR TREATMENT OF DERMATOPHYTOSIS ARANDOMISED CONTROL TRIAL IN CHENGALPATTU TAMilNADU INDIA - NILCTRI/2025/03/082290
Salicylic Acid Versus Cryotherapy for the Treatment of HPV1-induced Plantar WartsSalicylic Acid Versus Cryotherapy for the Treatment of HPV1-induced Plantar Warts: a Randomized Controlled TrialNCT05617950
Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic WomenThe Efficacy of Salicylic Acid Peels Combined With 4% Hydroquinone Cream Versus 4% Hydroquinone Cream Alone in the Treatment of Hispanic Women With Moderate to Severe MelasmaNCT00616239
Pyruvic Acid Versus Salicylic Acid Preparation in Treatment of Plantar WartsComparison of 70% Pyruvic Acid Solution and Duofilm Solution in Treatment of Plantar WartNCT02151630
Efficacy and Safety of a Preparation Containing an Antibiotic and Anti-Inflammatory Agent in Acne VulgarisTopical Clindamycin Salicylic Acid Preparation for the Treatment of Acne VulgarisNCT00361322
Cryotherapy versus salicylic acid for the treatment of verrucae: a randomised controlled trial. - EVerTCryotherapy versus salicylic acid for the treatment of verrucae: a randomised controlled trial. - EVerTEUCTR2004-000905-24-GB
Cryotherapy versus Salicylic Acid with Monochloracetic Acid for the Treatment of Verrucae: A Randomised Controlled TrialISRCTN78267267
Use of Acetyl Salicylic Acid and Terbutalin in Assisted Reproductive Techniques (ART)Use of Acetylsalicylic Acid and Terbutalin in ARTNCT00518141
U0289-405: An Open-Label, 12-Week Study to Evaluate the Efficacy and Safety of the Acne System (Benzoyl Peroxide 2.5%, Salicylic Acid 0.5%) in Subjects With AcneAn Open-Label, 12-Week Study to Evaluate the Efficacy and Safety of the Acne System (Benzoyl Peroxide 2.5%, Salicylic Acid 0.5%) in Subjects With AcneNCT01446237
Study to Compare the Effect of a Combination of Dipyridamole With Sustained Release and Acetyl Salicylic Acid (Aggrenox®) on the Performance Relevant to Safety and on the General Condition of Healthy VolunteersPlacebo-controlled, Randomized, Double-blind Study Comparing the Effect of a Combination of 200 mg Dipyridamole With Sustained Release and 25 mg Acetyl Salicylic Acid (Aggrenox®) on the Performance Relevant to Safety and on the General Condition of Volunteers and 10 Days of Treatment Alone and in Combination With Alcohol (Study no. 591002)NCT02278302